Epithelial and endothelial monolayers are multicellular sheets that form barriers between the
'outside'and 'inside'of tissues. Cell-cell junctions, made by adherens junctions, tight junctions …

The emergence of collagen I in vertebrates resulted in a dramatic increase in the stiffness of
the extracellular environment, supporting long-range force propagation and the …

Non-muscle myosin 2A (NM2A) is a motor cytoskeletal enzyme with crucial importance from
the early stages of development until adulthood. Due to its capacity to convert chemical …

Cells tune adherens junction dynamics to regulate epithelial integrity in diverse (patho)
physiological processes, including cancer metastasis. We hypothesized that the spatially …

The mechanisms that regulate the spatial sorting of nonmuscle myosins-2 (NM2) isoforms
and couple them mechanically to the plasma membrane are unclear. Here we show that the …

Tight and adherens junctions are specialized sites of cell-cell interaction in epithelia and
endothelia, and are involved in barrier, adhesion, and signaling functions. These functions …

Considerable progress has been made in our knowledge of the morphological and
functional varieties of anchoring junctions. Cell-cell adhesion contacts consist of discrete …

While much work has been done in the design of biomaterials to control integrin‐mediated
adhesion, less emphasis has been put on functionalization of materials with cadherin …

Liquid-liquid phase separation (LLPS) is involved in various dynamic biological
phenomena. In epithelial cells, dynamic regulation of junctional actin filaments tethered to …

In the process of mechanotransduction, the cells in the body perceive and interpret
mechanical stimuli to maintain tissue homeostasis and respond to the environmental …