Hearing loss has an extremely high prevalence worldwide and brings incredible economic
and social burdens. Mechanisms such as epigenetics are profoundly involved in the …

Rett syndrome (RTT) is a rare neurodevelopmental disorder that is usually caused by
mutations of the MECP2 gene. Patients with RTT suffer from severe deficits in motor …

Neuroinflammation is an escalation factor shared by a vast range of central nervous system
(CNS) pathologies, from neurodegenerative diseases to neuropsychiatric disorders. CNS …

Forkhead box G1 (FOXG1) has important functions in neuronal differentiation and balances
excitatory/inhibitory network activity. Thus far, molecular processes underlying FOXG1 …

The transcription factor FOXG1 serves pleiotropic functions in brain development ranging
from the regulation of precursor proliferation to the control of cortical circuit formation. Loss …

FOXG1 is an ancient transcription factor gene mastering telencephalic development. A
number of distinct structural FOXG1 mutations lead to the “FOXG1 syndrome”, a complex …

Foxg1 masters telencephalic development via a pleiotropic control over its progression.
Expressed within the central nervous system (CNS), L1 retrotransposons are implicated in …

Background Mainly known as a transcription factor patterning the rostral brain and
governing its histogenesis, FOXG1 has been also detected outside the nucleus; however …

Sizes of neuronal, astroglial and oligodendroglial complements forming the neonatal
cerebral cortex largely depend on rates at which pallial stem cells give rise to lineage …

Derailed gene expression programs within the developing nervous system, encompassing
both transcriptional and posttranscriptional processes, can cause diverse …