[PDF][PDF] Phytochemistry and pharmacology of Imperata cylindrica: A comprehensive review

P Nayim, AT Mbaveng, K Sudhir… - Invest Med Chem …, 2023 - researchgate.net
Background: Imperata cylindrica is a medicinal spice used in traditional medicine to cure
several ailments including cancer, wounds, hypertension, and inflammation. The current …

Fractionation and Characterization of Triterpenoids from Vaccinium vitis-idaea L. Cuticular Waxes and Their Potential as Anticancer Agents

G Vilkickyte, V Petrikaite, M Marksa, L Ivanauskas… - Antioxidants, 2023 - mdpi.com
Fruit and leaf cuticular waxes are valuable source materials for the isolation of triterpenoids
that can be applied as natural antioxidants and anticancer agents. The present study aimed …

Brazilian red propolis: Extracts production, physicochemical characterization, and cytotoxicity profile for antitumor activity

FMA de Carvalho, JK Schneider, CVF de Jesus… - Biomolecules, 2020 - mdpi.com
Brazilian red propolis has been proposed as a new source of compounds with cytotoxic
activity. Red propolis is a resinous material of vegetal origin, synthesized from the bees of …

Lupeol and Paclitaxel cooperate in hindering hypoxia induced vasculogenic mimicry via suppression of HIF-1α-EphA2-Laminin-5γ2 network in human oral cancer

D Saha, D Mitra, N Alam, S Sen, SM Mustafi… - Journal of Cell …, 2023 - Springer
Vasculogenic mimicry (VM), defined as an endothelial cell independent alternative
mechanism of blood and nutrient supply by dysregulated tumor cells, is associated with poor …

Medicinal plants used in managing diseases of the respiratory system among the Luo community: an appraisal of Kisumu East Sub-County, Kenya

JK Mailu, JM Nguta, JM Mbaria, MO Okumu - Chinese Medicine, 2020 - Springer
Background Poor access to healthcare in rural communities causes many people to seek
herbalists who use medicinal plants for the treatment of various disease conditions. Most …

Cytotoxic alkaloids from the root of Zanthoxylum paracanthum (mildbr) Kokwaro

LK Omosa, VA Nchiozem-Ngnitedem… - Natural Product …, 2022 - Taylor & Francis
Chemical investigation of the root of Zanthoxylum paracanthum afforded 1 new alkamide
derivative,(2 E, 4 E)-6-oxo-N-isobutyldeca-2, 4-dienamide (1) together with 10 known …

A review of natural products and small‐molecule therapeutics acting on central nervous system malignancies: Approaches for drug development, targeting pathways …

A Pasdaran, ID Grice, A Hamedi - Drug Development Research, 2024 - Wiley Online Library
Abstract In 2021, the World Health Organization released the fifth edition of the central
nervous system (CNS) tumor classification. This classification uses histopathology and …

Cytotoxicity of fagaramide derivative and canthin-6-one from Zanthoxylum (Rutaceae) species against multidrug resistant leukemia cells

LK Omosa, GM Mbogo, E Korir, R Omole… - Natural Product …, 2021 - Taylor & Francis
In our continuous search for cytotoxic compounds from the genus Zanthoxylum,
chromatographic separation of the MeOH/CH2Cl2 (1: 1) extract of Z. chalybeum yielded one …

Therapeutic potential of the genus Zanthoxylum phytochemicals: A theoretical ADME/Tox analysis

EN Wekesa, NM Kimani, SN Kituyi, LK Omosa… - South African Journal of …, 2023 - Elsevier
Natural products (NPs) are essential in the search for new drugs to treat a wide range of
diseases, including infectious and malignant disorders. However, despite the discovery of …

[HTML][HTML] Cytotoxic flavonoids from the seeds of Dracaena steudneri Engl against leukemia cancer cell lines

VA Nchiozem-Ngnitedem, LK Omosa, S Derese… - Phytomedicine Plus, 2022 - Elsevier
Background Leukemia is the most common type of childhood cancer. Numerous flavonoids
isolated from plants have been reported as potential chemotherapeutic agents against …