Antioxidant and Prooxidant Nanozymes: From Cellular Redox Regulation to Next‐Generation Therapeutics

N Singh, GR Sherin, G Mugesh - Angewandte Chemie, 2023 - Wiley Online Library
Nanozymes, nanomaterials with enzyme‐mimicking activity, have attracted tremendous
interest in recent years owing to their ability to replace natural enzymes in various …

Synthesis, bioactive properties, and biomedical applications of intrinsically therapeutic nanoparticles for disease treatment

DD Nguyen, JY Lai - Chemical Engineering Journal, 2022 - Elsevier
Intrinsically therapeutic nanoparticles (ITNPs) are a special class of nanomaterials with
capabilities of self-triggering bioactive activities (without drug) when interacting with …

An H2S‐BMP6 Dual‐Loading System with Regulating Yap/Taz and Jun Pathway for Synergistic Critical Limb Ischemia Salvaging Therapy

J Hu, Z Xu, D Liao, Y Jiang, H Pu, Z Wu… - Advanced …, 2023 - Wiley Online Library
Critical limb ischemia, the final course of peripheral artery disease, is characterized by an
insufficient supply of blood flow and excessive oxidative stress. H2S molecular therapy …

Biocatalytic and antioxidant nanostructures for ROS scavenging and biotherapeutics

L Wang, B Zhu, Y Deng, T Li, Q Tian… - Advanced Functional …, 2021 - Wiley Online Library
In human systems, reactive oxygen species (ROS) significantly affect different physiological
activities and play critical roles in diverse living processes. It is widely known that excessive …

Redox active cerium oxide nanoparticles: current status and burning issues

MS Lord, JF Berret, S Singh, A Vinu, AS Karakoti - Small, 2021 - Wiley Online Library
Research on cerium oxide nanoparticles (nanoceria) has captivated the scientific community
due to their unique physical and chemical properties, such as redox activity and oxygen …

Nanoceria, the versatile nanoparticles: Promising biomedical applications

MA Saifi, S Seal, C Godugu - Journal of Controlled Release, 2021 - Elsevier
Nanotechnology has been a boon for the biomedical field due to the freedom it provides for
tailoring of pharmacokinetic properties of different drug molecules. Nanomedicine is the …

Diabetic bone regeneration with nanoceria-tailored scaffolds by recapitulating cellular microenvironment: activating integrin/TGF-β co-signaling of MSCs while …

RK Singh, DS Yoon, N Mandakhbayar, C Li, AG Kurian… - Biomaterials, 2022 - Elsevier
Regenerating defective bone in patients with diabetes mellitus remains a significant
challenge due to high blood glucose level and oxidative stress. Here we aim to tackle this …

“Hard” ceramics for “Soft” tissue engineering: Paradox or opportunity?

S Kargozar, RK Singh, HW Kim, F Baino - Acta Biomaterialia, 2020 - Elsevier
Tissue engineering provides great possibilities to manage tissue damages and injuries in
modern medicine. The involvement of hard biocompatible materials in tissue engineering …

Nanotheranostics for the management of hepatic ischemia‐reperfusion injury

Y Guan, W Yao, K Yi, C Zheng, S Lv, Y Tao, Z Hei, M Li - Small, 2021 - Wiley Online Library
Hepatic ischemia‐reperfusion injury (IRI), in which an insufficient oxygen supply followed by
reperfusion leads to an inflammatory network and oxidative stress in disease tissue to cause …

Electrospun nanofibers for improved angiogenesis: promises for tissue engineering applications

S Nazarnezhad, F Baino, HW Kim, TJ Webster… - Nanomaterials, 2020 - mdpi.com
Angiogenesis (or the development of new blood vessels) is a key event in tissue
engineering and regenerative medicine; thus, a number of biomaterials have been …