Alzheimer's disease (AD) and Parkinson's disease (PD) are the most prevalent
neurodegenerative diseases, affecting millions and costing billions each year in the United …

For years, it has been reported that Alzheimer's disease (AD) is the most common cause of
dementia. Various external and internal factors may contribute to the early onset of AD. This …

Alzheimer's disease (AD) is a neurodegenerative disease whose various pathophysiological
aspects are still being investigated. Recently, it has been hypothesized that AD may be …

Alzheimer's disease is a common and devastating disease characterized by aggregation of
the amyloid-β peptide. However, we know relatively little about the underlying molecular …

In the initiation or exacerbation of Alzheimer disease, the dissemination of oral
microorganisms into the brain tissue or the low‐level systemic inflammation have been …

Neurodegenerative diseases are increasing in number, given that the general global
population is becoming older. They manifest themselves through mechanisms that are not …

It is well accepted that CNS inflammation has a role in the progression of chronic
neurodegenerative disease, although the mechanisms through which this occurs are still …

Alzheimer's disease is associated with cerebral accumulation of amyloid-β peptide and
hyperphosphorylated tau. In the past 28 years, huge efforts have been made in attempting to …

Previously, the contribution of peripheral infection to cognitive decline was largely
overlooked however, the past 15 years have established a key role for infectious pathogens …

Mitochondria are essential organelles for many aspects of cellular homeostasis, including
energy harvesting through oxidative phosphorylation. Alterations of mitochondrial function …