International consensus statement on allergy and rhinology: Allergic rhinitis–2023

SK Wise, C Damask, LT Roland, C Ebert… - International forum of …, 2023 - Wiley Online Library
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Biologics and airway remodeling in severe asthma

G Varricchi, S Ferri, J Pepys, R Poto, G Spadaro… - Allergy, 2022 - Wiley Online Library
Asthma is a chronic inflammatory airway disease resulting in airflow obstruction, which in
part can become irreversible to conventional therapies, defining the concept of airway …

Type 2 immunity in the skin and lungs

CA Akdis, PD Arkwright, MC Brüggen, W Busse… - Allergy, 2020 - Wiley Online Library
There has been extensive progress in understanding the cellular and molecular
mechanisms of inflammation and immune regulation in allergic diseases of the skin and …

EAACI Biologicals Guidelines—Recommendations for severe asthma

I Agache, CA Akdis, M Akdis, GW Canonica, T Casale… - Allergy, 2021 - Wiley Online Library
Severe asthma imposes a significant burden on patients, families and healthcare systems.
Management is difficult, due to disease heterogeneity, co‐morbidities, complexity in care …

Cellular and molecular mechanisms of allergic asthma

ZI Komlósi, W van de Veen, N Kovács, G Szűcs… - Molecular aspects of …, 2022 - Elsevier
Asthma is a chronic disease of the airways, which affects more than 350 million people
worldwide. It is the most common chronic disease in children, affecting at least 30 million …

Anti‐IL‐5 therapies for asthma

HA Farne, A Wilson, S Milan, E Banchoff… - Cochrane Database …, 2022 - cochranelibrary.com
Antecedentes Esta la segunda actualización de una revisión publicada anteriormente en la
Biblioteca Cochrane (2015, primera actualización en 2017). La interleucina 5 (IL‐5) es la …

Advances and recent developments in asthma in 2020

L Cevhertas, I Ogulur, DJ Maurer, D Burla, M Ding… - Allergy, 2020 - Wiley Online Library
In this review, we discuss recent publications on asthma and review the studies that have
reported on the different aspects of the prevalence, risk factors and prevention, mechanisms …

Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma

H Breiteneder, YQ Peng, I Agache, Z Diamant… - Allergy, 2020 - Wiley Online Library
Modern health care requires a proactive and individualized response to diseases,
combining precision diagnosis and personalized treatment. Accordingly, the approach to …

[HTML][HTML] Integrated safety and efficacy among patients receiving benralizumab for up to 5 years

S Korn, A Bourdin, G Chupp, BG Cosio… - The Journal of Allergy …, 2021 - Elsevier
Background Benralizumab is an IL-5Rα–directed monoclonal antibody indicated for patients
with severe, uncontrolled eosinophilic asthma. Objective To evaluate the long-term safety …

Real‐world efficacy of treatment with benralizumab, dupilumab, mepolizumab and reslizumab for severe asthma: A systematic review and meta‐analysis

D Charles, J Shanley, SN Temple… - Clinical & …, 2022 - Wiley Online Library
Background Severe asthma is a major cause of morbidity. Some patients may benefit from
biological therapies. Most evaluations of these treatments are derived from randomized …