The method of supersaturation for achieving high drug loads in lipid-based formulations is
under exploited and relatively unexplored, especially in the case of solid-state lipid-based …

Compatibility between diazepam (DZP), a benzodiazepine drug used for the treatment of
anxiety, and tablet excipients has been investigated by thermal analysis (differential …

The purpose of this study was to investigate the thermal properties of polymeric
microspheres and their modified with drug molecules and silica gel counterparts under …

Background: A series of different experimental approaches was applied in Zincum
metallicum (Zinc met.) samples and lactose controls. Experiments were designed to …

This paper deals with the application of fast screening tools such as FTIR, thermal analysis
and DSC in the evaluation of compatibility between the active pharmaceutical ingredient …

The main objective of this work was to use the Differential Scanning Calorimetry (DSC) and
FTIR spectroscopy to study the possible drug-drug or drug-excipient (s) interaction in case of …

The thermal stability, purity and compatibility of some fluoroquinolones, including
sparfloxacin HCl (SPAR), besifloxacin HCl (BESI), gemifloxacin mesylate (GEM), and their …

This work identifies the cause of sticking of granules in an industrial process of tableting.
Retrospective multivariate statistical analysis of industrial scale batches' records (PLS …

A detailed thermal analysis investigation of title BCS class II active pharmaceutical
ingredients with low solubility and high permeability and known polymorphism were …

Donepezil (Don) is one of the main compounds used in the therapy of Alzheimer's disease.
In this study, donepezil hydrochloride was investigated for solid-state compatibility with …