Synthesis of esters by immobilized-lipase-catalyzed condensation reaction of sugars and fatty acids in water-miscible organic solvent
S Adachi, T Kobayashi - Journal of bioscience and bioengineering, 2005 - Elsevier
A lipase-catalyzed condensation reaction in an organic solvent is a promising means of
synthesizing esters. Reaction equilibrium constant, which is usually defined on the basis of …
synthesizing esters. Reaction equilibrium constant, which is usually defined on the basis of …
Kinetic Resolution of Profens by Enantioselective Esterification Catalyzed by Candida antarctica and Candida rugosa Lipases
ABSTRACT Profens (2‐arylpropionic acids) are known as one of the major nonsteroidal
antiinflammatory drugs (NSAIDs) used in the treatment of inflammation associated with …
antiinflammatory drugs (NSAIDs) used in the treatment of inflammation associated with …
Preparation and characterization of immobilized lipase from Pseudomonas cepacia onto magnetic cellulose nanocrystals
Magnetic cellulose nanocrystals (MCNCs) were prepared and used as an enzyme support
for immobilization of Pseudomonas cepacialipase (PCL). PCL was successfully immobilized …
for immobilization of Pseudomonas cepacialipase (PCL). PCL was successfully immobilized …
Towards sustainable kinetic resolution, a combination of bio-catalysis, flow chemistry and bio-based solvents
A Iemhoff, J Sherwood, CR McElroy, AJ Hunt - Green Chemistry, 2018 - pubs.rsc.org
The esterification of 2-phenylpropionic acid was investigated as a model system for enzyme
catalysed (CALB, Novozyme 435) reactions in bio-based solvents. A multi-parameter …
catalysed (CALB, Novozyme 435) reactions in bio-based solvents. A multi-parameter …
Enantioselective esterification of ibuprofen with ethanol as reactant and solvent catalyzed by immobilized lipase: experimental and molecular modeling aspects
ML Foresti, M Galle, ML Ferreira… - Journal of Chemical …, 2009 - Wiley Online Library
BACKGROUND: In recent years enantioselective esterification of racemic ibuprofen
performed in organic co‐solvent media such as isooctane and cyclohexane and catalyzed …
performed in organic co‐solvent media such as isooctane and cyclohexane and catalyzed …
Performance of free Candida antarctica lipase B in the enantioselective esterification of (R)-ketoprofen
AL Ong, AH Kamaruddin, S Bhatia, WS Long… - Enzyme and microbial …, 2006 - Elsevier
The performance of free Candida antarctica lipase B (CALB) in a mixed solvent system for
enantioselective esterification of (R)-ketoprofen, leaving the target product (S)-ketoprofen in …
enantioselective esterification of (R)-ketoprofen, leaving the target product (S)-ketoprofen in …
Current technologies for the production of (S)-ketoprofen: Process perspective
AL Ong, AH Kamaruddin, S Bhatia - Process Biochemistry, 2005 - Elsevier
Ketoprofen (2-(3-benzoylphenyl)-propionic acid), belongs to the family of 2-arylpropionic
acids (profens), is one of the nonstreroidal anti-inflammatory drugs. The production of single …
acids (profens), is one of the nonstreroidal anti-inflammatory drugs. The production of single …
Towards a green enantiomeric esterification of R/S-ketoprofen: A theoretical and experimental investigation
Abstract Methanol, ethanol, 1-and 2-propanol were used as reactants and solvents in the
esterification of R/S-ketoprofen catalyzed with Novozym® 435. The interaction of the …
esterification of R/S-ketoprofen catalyzed with Novozym® 435. The interaction of the …
Enantioseparation of (R,S)‐ketoprofen using Candida antarctica lipase B in an enzymatic membrane reactor
AL Ong, AH Kamaruddin, S Bhatia… - Journal of separation …, 2008 - Wiley Online Library
An enzymatic membrane reactor (EMR) for enantioseparation of (R, S)‐ketoprofen via
Candida antarctica lipase B (CALB) as biocatalyst was investigated. A comparative study of …
Candida antarctica lipase B (CALB) as biocatalyst was investigated. A comparative study of …
Enzymatic production of enantiopure ketoprofen in a solvent-free two-phase system
JN Jin, SH Lee, SB Lee - Journal of Molecular Catalysis B: Enzymatic, 2003 - Elsevier
Enzymatic hydrolysis conducted in a medium composed of solely substrate is considered to
resolve racemic ketoprofen esters. In a system composed of two components, the pure liquid …
resolve racemic ketoprofen esters. In a system composed of two components, the pure liquid …