Ischemic heart disease pathophysiology paradigms overview: from plaque activation to microvascular dysfunction

P Severino, A D'Amato, M Pucci, F Infusino… - International journal of …, 2020 - mdpi.com
Ischemic heart disease still represents a large burden on individuals and health care
resources worldwide. By conventions, it is equated with atherosclerotic plaque due to flow …

Ischemic heart disease and heart failure: role of coronary ion channels

P Severino, A D'Amato, M Pucci, F Infusino… - International journal of …, 2020 - mdpi.com
Heart failure is a complex syndrome responsible for high rates of death and hospitalization.
Ischemic heart disease is one of the most frequent causes of heart failure and it is normally …

Advanced heart failure and end-stage heart failure: does a difference exist

P Severino, PJ Mather, M Pucci, A D'Amato… - Diagnostics, 2019 - mdpi.com
Advanced heart failure (AdHF) represents a challenging aspect of heart failure patients.
Because of worsening clinical symptoms, high rates of re-hospitalization and mortality, AdHF …

The Effect of the Teach‐Back Method on Knowledge, Performance, Readmission, and Quality of Life in Heart Failure Patients

A Rahmani, A Vahedian-Azimi… - Cardiology research …, 2020 - Wiley Online Library
Background. Among chronic diseases, heart failure has always been a serious challenge
imposing high costs on health systems and societies. Therefore, nurses should adopt new …

Heart failure pharmacological management: gaps and current perspectives

P Severino, A D'Amato, S Prosperi, V Myftari… - Journal of clinical …, 2023 - mdpi.com
Proper therapeutic management of patients with heart failure (HF) is a major challenge for
cardiologists. Current guidelines indicate to start therapy with angiotensin converting …

Reduction in heart failure hospitalization rate during coronavirus disease 19 pandemic outbreak

P Severino, A D'Amato, A Saglietto… - ESC Heart …, 2020 - Wiley Online Library
Aims The recent coronavirus disease 19 (COVID‐19) pandemic outbreak forced the
adoption of restraint measures, which modified the hospital admission patterns for several …

Do the current guidelines for heart failure diagnosis and treatment fit with clinical complexity?

P Severino, A D'Amato, S Prosperi, A Dei Cas… - Journal of Clinical …, 2022 - mdpi.com
Heart failure (HF) is a clinical syndrome defined by specific symptoms and signs due to
structural and/or functional heart abnormalities, which lead to inadequate cardiac output …

The effects of Dapagliflozin in a real-world population of HFrEF patients with different hemodynamic profiles: worse is better

F Loria, P Mone, A Rispoli, R Di Fonzo… - Cardiovascular …, 2024 - Springer
Abstract Background Sodium-Glucose Cotransporter-2 inhibitors (SGLT2i) represent a deep
revolution of the therapeutic approach to heart failure (HF), preventing its insurgence but …

C-reactive protein as a risk marker for post-infarct heart failure over a multi-year period

I Świątkiewicz, P Magielski, J Kubica - International Journal of Molecular …, 2021 - mdpi.com
Inflammatory activation during acute ST-elevation myocardial infarction (STEMI) can
contribute to post-infarct heart failure (HF). This study aimed to determine prognostic value of …

Myocardial tissue characterization in heart failure with preserved ejection fraction: from histopathology and cardiac magnetic resonance findings to therapeutic targets

P Severino, A D'Amato, S Prosperi, F Fanisio… - International Journal of …, 2021 - mdpi.com
Heart failure with preserved ejection fraction (HFpEF) is a complex clinical syndrome
responsible for high mortality and morbidity rates. It has an ever growing social and …