Dysregulation of TCTP in biological processes and diseases

UA Bommer, A Telerman - Cells, 2020 - mdpi.com
Translationally controlled tumor protein (TCTP), also called histamine releasing factor (HRF)
or fortilin, is a multifunctional protein present in almost all eukaryotic organisms. TCTP is …

Safety evaluation of Neurospora crassa mycoprotein for use as a novel meat alternative and enhancer

BM Bartholomai, KM Ruwe, J Thurston, P Jha… - Food and Chemical …, 2022 - Elsevier
Cultivation of filamentous fungi to produce sustainable, nutrient rich meat replacements has
recently attracted significant commercial and research interest. Here, we report evidence for …

The translational controlled tumour protein TCTP: biological functions and regulation

UA Bommer - TCTP/tpt1-Remodeling Signaling from Stem Cell to …, 2017 - Springer
Abstract The Translational Controlled Tumour Protein TCTP (gene symbol TPT1, also called
P21, P23, Q23, fortilin or histamine-releasing factor, HRF) is a highly conserved protein …

Long noncoding RNA HOTAIR interacts with Y-Box Protein-1 (YBX1) to regulate cell proliferation

S Li, Q Xiong, M Chen, B Wang, X Yang… - Life science …, 2021 - life-science-alliance.org
HOTAIR is a long noncoding RNA (lncRNA) which serves as an important factor regulating
diverse processes linked with cancer development. Here, we used comprehensive …

Acetylation of translationally controlled tumor protein promotes its degradation through chaperone-mediated autophagy

A Bonhoure, A Vallentin, M Martin… - European journal of cell …, 2017 - Elsevier
Translationally controlled tumor protein (Tpt1/TCTP) is a multi-functional cytosolic protein
whose cellular levels are finely tuned. TCTP regulates protein behavior by favoring …

TCTP regulates genotoxic stress and tumorigenicity via intercellular vesicular signaling

R Amson, A Senff-Ribeiro, T Karafin, A Lespagnol… - EMBO …, 2024 - embopress.org
Oncogenic intercellular signaling is regulated by extracellular vesicles (EVs), but the
underlying mechanisms remain mostly unclear. Since TCTP (translationally controlled tumor …

Tumor reversion: a dream or a reality

A Tripathi, A Kashyap, G Tripathi, J Yadav, R Bibban… - Biomarker …, 2021 - Springer
Reversion of tumor to a normal differentiated cell once considered a dream is now at the
brink of becoming a reality. Different layers of molecules/events such as microRNAs …

Molecular cloning and functional characterisation of NLRX1 in grass carp (Ctenopharyngodon idella)

P Chu, L He, Y Li, R Huang, L Liao, Y Li, Z Zhu… - Fish & shellfish …, 2018 - Elsevier
The nucleotide-binding domain and leucine-rich-repeat-containing (NLR) proteins regulate
innate immunity. Although the positive regulatory impact of NLRs is clear, their inhibitory …

Identification of a Specific Translational Machinery via TCTP–EF1A2 Interaction Regulating NF1-associated Tumor Growth by Affinity Purification and Data …

D Kobayashi, T Tokuda, K Sato, H Okanishi… - Molecular & Cellular …, 2019 - ASBMB
Neurofibromatosis type 1 (NF1) is an autosomal dominant disease that predisposes
individuals to developing benign neurofibromas and malignant peripheral nerve sheath …

Current understanding of the TCTP interactome

S Li, F Ge - TCTP/tpt1-Remodeling Signaling from Stem Cell to …, 2017 - Springer
Evolutionarily conserved and pleiotropic, the translationally controlled tumor protein (TCTP)
is a housekeeping protein present in eukaryotic organisms. It plays an important role in …