Peptide antimicrobial agents
H Jenssen, P Hamill, REW Hancock - Clinical microbiology …, 2006 - Am Soc Microbiol
Antimicrobial host defense peptides are produced by all complex organisms as well as
some microbes and have diverse and complex antimicrobial activities. Collectively these …
some microbes and have diverse and complex antimicrobial activities. Collectively these …
Focus on antivirally active sulfated polysaccharides: from structure–activity analysis to clinical evaluation
T Ghosh, K Chattopadhyay, M Marschall… - …, 2009 - academic.oup.com
In recent years, many compounds having potent antiviral activity in cell culture have been
detected and some of these compounds are currently undergoing either preclinical or …
detected and some of these compounds are currently undergoing either preclinical or …
Antiviral activity of lambda-carrageenan against influenza viruses and severe acute respiratory syndrome coronavirus 2
Y Jang, H Shin, MK Lee, OS Kwon, JS Shin, Y Kim… - Scientific reports, 2021 - nature.com
Influenza virus and coronavirus, belonging to enveloped RNA viruses, are major causes of
human respiratory diseases. The aim of this study was to investigate the broad spectrum …
human respiratory diseases. The aim of this study was to investigate the broad spectrum …
Targeting heparin and heparan sulfate protein interactions
Heparin and heparan sulfate glycosaminoglycans are long, linear polysaccharides that are
made up of alternating dissacharide sequences of sulfated uronic acid and amino sugars …
made up of alternating dissacharide sequences of sulfated uronic acid and amino sugars …
Interactions between heparan sulfate and proteins—design and functional implications
Heparan sulfate (HS) proteoglycans at cell surfaces and in the extracellular matrix of most
animal tissues are essential in development and homeostasis, and variously implicated in …
animal tissues are essential in development and homeostasis, and variously implicated in …
A small molecule inhibits virion attachment to heparan sulfate-or sialic acid-containing glycans
CC Colpitts, LM Schang - Journal of virology, 2014 - Am Soc Microbiol
Primary attachment to cellular glycans is a critical entry step for most human viruses. Some
viruses, such as herpes simplex virus type 1 (HSV-1) and hepatitis C virus (HCV), bind to …
viruses, such as herpes simplex virus type 1 (HSV-1) and hepatitis C virus (HCV), bind to …
Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection
Certain sulfated glycans, including those from marine sources, can show potential effects
against SARS-CoV-2. Here, a new fucosylated chondroitin sulfate (FucCS) from the sea …
against SARS-CoV-2. Here, a new fucosylated chondroitin sulfate (FucCS) from the sea …
Selective transmission of CCR5-utilizing HIV-1: the'gatekeeper'problem resolved?
L Margolis, R Shattock - Nature Reviews Microbiology, 2006 - nature.com
Understanding the mechanisms of HIV-1 transmission is crucial for the development of
effective preventive microbicides and vaccine strategies, and remains one of the main goals …
effective preventive microbicides and vaccine strategies, and remains one of the main goals …
HIV-1 gp120 induces TLR2-and TLR4-mediated innate immune activation in human female genital epithelium
A Nazli, JK Kafka, VH Ferreira, V Anipindi… - The Journal of …, 2013 - journals.aai.org
Although women constitute half of all HIV-1–infected people worldwide (UNAIDS World
AIDS Day Report, 2011), the earliest events in the female reproductive tract (FRT) during …
AIDS Day Report, 2011), the earliest events in the female reproductive tract (FRT) during …
Human immunodeficiency virus and heparan sulfate: from attachment to entry inhibition
BJ Connell, H Lortat-Jacob - Frontiers in immunology, 2013 - frontiersin.org
By targeting cells that provide protection against infection, HIV-1 causes acquired
immunodeficiency syndrome. Infection starts when gp120, the viral envelope glycoprotein …
immunodeficiency syndrome. Infection starts when gp120, the viral envelope glycoprotein …