Persistent organic pollutants (POPs) encompass an array of anthropogenic organic and
elemental substances and their degradation and metabolic byproducts that have been found …

The objective of this review is to provide an overview of recent studies demonstrating the
endocrine disrupting (ED) effects of brominated flame retardants (BFRs), while highlighting …

Brominated flame retardants (BFR) are endocrine disrupters in experimental systems, both
in vitro and in vivo. Although BFR effects on thyroid hormones are well confirmed, studies of …

Despite documented widespread human exposure to polybrominated diphenyl ethers
(PBDEs) through dietary intake and contact with or inhalation of indoor dust, along with …

Polybrominated diphenyl ethers (PBDEs) have been widely used as flame retardants. The
structurally related hydroxylated PBDEs (OH-PBDEs) and methoxylated PBDEs (MeO …

Background Polybrominated diphenyl ether (PBDE) flame retardants have been implicated
as disruptors of the hypothalamic-pituitary-thyroid axis. Animals exposed to PBDEs may …

In this study, the endocrine‐disrupting (ED) potency of metabolites from brominated flame
retardants (BFRs) was determined. Metabolites were obtained by incubating single‐parent …

Background Oxidative metabolism, resulting in the formation of hydroxylated polybrominated
diphenyl ether (PBDE) metabolites, may enhance the neurotoxic potential of brominated …

Thyroid hormones (THs) are required for normal brain and somatic development and for the
proper regulation of physiology in both children and adults. Thyroid function is controlled by …

Background and aim Endocrine disrupting chemicals (EDCs) constitute a major public
health concern because they can induce a large spectrum of adverse effects by interfering …