Juvenile myoclonic epilepsy: a system disorder of the brain

P Wolf, EMT Yacubian, G Avanzini, T Sander… - Epilepsy research, 2015 - Elsevier
The prevailing understanding of generalized epilepsy is shaped by the traditional definition
that “the responsible neuronal discharge takes place, if not throughout the entire grey matter …

[HTML][HTML] Early predictors of outcome in newly diagnosed epilepsy

R Mohanraj, MJ Brodie - Seizure, 2013 - Elsevier
Longitudinal studies of newly diagnosed epilepsy in children and adults have identified
prognostic factors that allow early identification of patients whose seizures are likely to …

Prognosis of juvenile myoclonic epilepsy 45 years after onset: seizure outcome and predictors

P Senf, B Schmitz, M Holtkamp, D Janz - Neurology, 2013 - AAN Enterprises
Objectives: Juvenile myoclonic epilepsy (JME) is the most common idiopathic generalized
epilepsy subsyndrome, contributing to approximately 3% to 11% of adolescent and adult …

The prognosis of idiopathic generalized epilepsy

U Seneviratne, M Cook, W D'Souza - Epilepsia, 2012 - Wiley Online Library
Prognosis describes the trajectory and long‐term outcome of a condition. Most studies
indicate a better prognosis in idiopathic generalized epilepsy (IGE) in comparison with other …

[HTML][HTML] Juvenile myoclonic epilepsy as a spectrum disorder: a focused review

B Baykan, P Wolf - Seizure, 2017 - Elsevier
In consequence of newer research juvenile myoclonic epilepsy (JME) is no longer seen as a
homogeneous disease. The causes of the existing variance are only partially known yet. We …

[HTML][HTML] Juvenile myoclonic epilepsy: Challenges on its 60th anniversary

EM Yacubian - Seizure, 2017 - Elsevier
Purpose Since its initial 1957 description, juvenile myoclonic epilepsy (JME) has been
recognized as a common epileptic syndrome worldwide. Methods We reviewed a series of …

Epilepsy with generalized tonic–clonic seizures alone: electroclinical features and prognostic patterns

E Cerulli Irelli, J Gesche, S Schlabitz, F Fortunato… - …, 2024 - Wiley Online Library
Objective Epilepsy with generalized tonic–clonic seizures alone (GTCA) is a common but
poorly characterized idiopathic generalized epilepsy (IGE) syndrome. Hence, we …

Resistance to valproic acid as predictor of treatment resistance in genetic generalized epilepsies

J Gesche, M Khanevski, C Solberg, CP Beier - Epilepsia, 2017 - Wiley Online Library
This study aimed at defining clinical predictors of drug resistance in adults with genetic
generalized epilepsy (GGE) who were treated with a broad spectrum of antiepileptic drugs …

[HTML][HTML] Seizure outcome in 175 patients with juvenile myoclonic epilepsy–a long-term observational study

J Höfler, I Unterberger, J Dobesberger, G Kuchukhidze… - Epilepsy research, 2014 - Elsevier
Introduction Juvenile myoclonic epilepsy (JME) is a genetic generalized epilepsy syndrome.
Under appropriate antiepileptic drugs (AED) up to 85% of patients become seizure-free, but …

Reflex epileptic mechanisms in humans: lessons about natural ictogenesis

P Wolf - Epilepsy & Behavior, 2017 - Elsevier
The definition of reflex epileptic seizures is that specific seizure types can be triggered by
certain sensory or cognitive stimuli. Simple triggers are sensory (most often visual, more …