Objectives To develop the first high-resolution, multi-scale model of cervical non-invasive
vagus nerve stimulation (nVNS) and to predict vagus fiber type activation, given clinically …

Objective The benefit of deep brain stimulation (DBS) for Parkinson disease (PD) may
depend on connectivity between the stimulation site and other brain regions, but which …

The hyperdirect pathway (HDP) represents the main glutamatergic input to the subthalamic
nucleus (STN), through which the motor and prefrontal cerebral cortex can modulate basal …

Background Transcranial magnetic stimulation (TMS) enables non-invasive modulation of
brain activity with both clinical and research applications, but fundamental questions remain …

Dystonia is a debilitating disease with few treatment options. One effective option is deep
brain stimulation (DBS) to the internal pallidum. While cervical and generalized forms of …

Objective. Deep brain stimulation (DBS) is a growing treatment option for movement and
psychiatric disorders. As DBS technology moves toward directional leads with increased …

Objective Responsive neurostimulation is an effective therapy for patients with refractory
mesial temporal lobe epilepsy. However, clinical outcomes are variable, few patients …

Background Deep brain stimulation (DBS) is an established clinical therapy and
computational models have played an important role in advancing the technology. Patient …

Medical imaging has played a major role in defining the general anatomical targets for deep
brain stimulation (DBS) therapies. However, specifics on the underlying brain circuitry that is …

Background Finding the optimal deep brain stimulation (DBS) parameters from a multitude
of possible combinations by trial and error is time consuming and requires highly trained …