The dynamics of the RNA world: insights and challenges
The RNA world hypothesis of the origin of life, in which RNA emerged as both enzyme and
information carrier, is receiving solid experimental support. The prebiotic synthesis of …
information carrier, is receiving solid experimental support. The prebiotic synthesis of …
Diversity begets stability: Sublinear growth and competitive coexistence across ecosystems
The worldwide loss of species diversity brings urgency to understanding how diverse
ecosystems maintain stability. Whereas early ecological ideas and classic observations …
ecosystems maintain stability. Whereas early ecological ideas and classic observations …
Ecology and evolution in the RNA world dynamics and stability of prebiotic replicator systems
As of today, the most credible scientific paradigm pertaining to the origin of life on Earth is
undoubtedly the RNA World scenario. It is built on the assumption that catalytically active …
undoubtedly the RNA World scenario. It is built on the assumption that catalytically active …
The origin of replicators and reproducers
E Szathmáry - … Transactions of the Royal Society B …, 2006 - royalsocietypublishing.org
Replicators are fundamental to the origin of life and evolvability. Their survival depends on
the accuracy of replication and the efficiency of growth relative to spontaneous decay …
the accuracy of replication and the efficiency of growth relative to spontaneous decay …
[图书][B] Динамические системы и модели в биологии
А Братусь, А Новожилов, А Платонов - 2022 - books.google.com
В этой книге дается изложение теории динамических систем и рассматриваются ее
приложения к биологии. Наряду с классическими математическими моделями …
приложения к биологии. Наряду с классическими математическими моделями …
Selection dynamics in autocatalytic systems: Templates replicating through binary ligation
PR Wills, SA Kauffman, BMR Stadler… - Bulletin of mathematical …, 1998 - Elsevier
The theory of autocatalytic binary ligation is reviewed within the context of a consistently
applied Michaelis-Menten quasi-steady-state approximation to obtain explicit analytical …
applied Michaelis-Menten quasi-steady-state approximation to obtain explicit analytical …
Stochastic parabolic growth promotes coexistence and a relaxed error threshold in RNA-like replicator populations
M Paczkó, E Szathmáry, A Szilágyi - Elife, 2024 - elifesciences.org
The RNA world hypothesis proposes that during the early evolution of life, primordial
genomes of the first self-propagating evolutionary units existed in the form of RNA-like …
genomes of the first self-propagating evolutionary units existed in the form of RNA-like …
Survival of replicators with parabolic growth tendency and exponential decay
I Scheuring, E Szathmáry - Journal of theoretical biology, 2001 - Elsevier
The claim that the competition of parabolically growing self-replicators leads to dynamically
stable coexistence was challenged by Lifson & Lifson [(1999). J. theor. Biol. 199, 425–433] …
stable coexistence was challenged by Lifson & Lifson [(1999). J. theor. Biol. 199, 425–433] …
Selection versus coexistence of parabolic replicators spreading on surfaces
G Von Kiedrowski, E Szathmáry - Selection, 2001 - akjournals.com
A common problem of non-enzymatic artificial replicator systems is product inhibition
leading to parabolic instead of exponential amplification. Exponential chemical replication of …
leading to parabolic instead of exponential amplification. Exponential chemical replication of …
Emergence of protocellular growth laws
T Rocheleau, S Rasmussen… - … of the Royal …, 2007 - royalsocietypublishing.org
Template-directed replication is known to obey a parabolic growth law due to product
inhibition (Sievers & Von Kiedrowski 1994 Nature 369, 221; Lee et al. 1996 Nature 382, 525; …
inhibition (Sievers & Von Kiedrowski 1994 Nature 369, 221; Lee et al. 1996 Nature 382, 525; …