Foundations of chemical reaction network theory

M Feinberg - 2019 - Springer
When I am called upon to teach fluid mechanics, I always show students a copy of Newton's
Principia. I do this for a number of reasons, not least of which is the connection I hope they …

[HTML][HTML] Inference of complex biological networks: distinguishability issues and optimization-based solutions

G Szederkényi, JR Banga, AA Alonso - BMC systems biology, 2011 - Springer
Background The inference of biological networks from high-throughput data has received
huge attention during the last decade and can be considered an important problem class in …

The effect of lumping and expanding on kinetic differential equations

AS Tomlin, G Li, H Rabitz, J Tóth - SIAM Journal on Applied Mathematics, 1997 - SIAM
Let us consider the differential equation ̇\bfy(t)=\bff(\bfy(t)) with an \bff from \bfR^N to \bfR^N
and suppose that there exists a transformation \bfh from \bfR^N to \bfR^̂N (̂N≤N) such …

Finding complex balanced and detailed balanced realizations of chemical reaction networks

G Szederkényi, KM Hangos - Journal of Mathematical Chemistry, 2011 - Springer
Reversibility, weak reversibility and deficiency, detailed and complex balancing are
generally not “encoded” in the kinetic differential equations but they are realization …

Biochemical reaction networks: an invitation for algebraic geometers

A Dickenstein - Mathematical congress of the Americas, 2016 - books.google.com
This article is a survey of the recent use of some techniques from computational algebraic
geometry to address mathematical challenges in systems biology.(Bio) chemical reaction …

[HTML][HTML] Morphisms of reaction networks that couple structure to function

L Cardelli - BMC systems biology, 2014 - Springer
Background The mechanisms underlying complex biological systems are routinely
represented as networks. Network kinetics is widely studied, and so is the connection …

Chemical reaction network approaches to biochemical systems theory

CPP Arceo, EC Jose, A Marin-Sanguino… - Mathematical …, 2015 - Elsevier
This paper provides a framework to represent a Biochemical Systems Theory (BST) model
(in either GMA or S-system form) as a chemical reaction network with power law kinetics …

[HTML][HTML] Inferring reaction systems from ordinary differential equations

F Fages, S Gay, S Soliman - Theoretical Computer Science, 2015 - Elsevier
Abstract In Mathematical Biology, many dynamical models of biochemical reaction systems
are presented with Ordinary Differential Equations (ODE). Once kinetic parameter values are …

Computing sparse and dense realizations of reaction kinetic systems

G Szederkényi - Journal of Mathematical Chemistry, 2010 - Springer
A numerical procedure for finding the sparsest and densest realization of a given reaction
network is proposed in this paper. The problem is formulated and solved in the framework of …

[HTML][HTML] From electric circuits to chemical networks

L Cardelli, M Tribastone, M Tschaikowski - Natural Computing, 2020 - Springer
Electric circuits manipulate electric charge and magnetic flux via a small set of discrete
components to implement useful functionality over continuous time-varying signals …