The use of life-saving antibiotics has long been plagued by the ability of pathogenic bacteria
to acquire and develop an array of antibiotic resistance mechanisms. The sum of these …

Aminoglycoside (AG) antibiotics are used to treat many Gram-negative and some Gram-
positive infections and, importantly, multidrug-resistant tuberculosis. Among various …

Antimicrobial resistance has been recognized as one of the most pressing public health and
societal issues of our times. The problem is most acute in gram-negative bacteria, where …

Carbapenemase-producing Enterobacteriaceae (CPE) were almost nonexistent up to the
1990s, but are today encountered routinely in hospitals and other healthcare facilities in …

(Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter
baumannii, Pseudomonas aeruginosa, and Enterobacter spp) pathogens, has become a …

Aminoglycoside antibiotics (AGAs) were developed at the dawn of the antibiotics era and
have significantly aided in the treatment of infectious diseases. Aminoglycosides have …

Aminoglycosides (AGs) are important antibacterial agents for the treatment of various
infections in humans and animals. Following extensive use of AGs in humans, food …

The rise of multidrug-resistant bacterial infections is a cause of global concern. There is an
urgent need to both revitalize antibacterial agents that are ineffective due to resistance while …

With the wide spread of multidrug-resistant bacteria, a variety of aminoglycosides have been
used in clinical practice as one of the effective options for antimicrobial combinations …

The objective of this study was to perform an inventory of the extended-spectrum-β-
lactamase (ESBL)-producing Enterobacteriaceae isolates responsible for infections in …