Aluminium (Al) is frequently accessible to animal and human populations to the extent that
intoxications may occur. Intake of Al is by inhalation of aerosols or particles, ingestion of …

Aluminium (Al) is clearly a powerful neurotoxicant. Considerable evidence exists that Al may
play a role in the aetiology or pathogenesis of Alzheimer's disease (AD), but whether the link …

Alzheimer's disease [AD] is the most common cause of dementia in North America. Despite
30+ years of intense investigation, the field lacks consensus regarding the etiology and …

The brain is a highly compartmentalized organ exceptionally susceptible to accumulation of
metabolic errors. Alzheimer's disease (AD) is the most prevalent neurodegenerative disease …

Deferoxamine mesylate (DFO) is an FDA-approved, hexadentate iron chelator routinely
used to alleviate systemic iron burden in thalassemia major and sickle cell patients. Iron …

Aluminium, an environmentally abundant non-redox trivalent cation has long been
implicated in the pathogenesis of Alzheimer's disease (AD). However, the definite …

Although aluminum is the most abundant metal in nature, it has no known biological
function. However, it is known that there is a causal role for aluminum in dialysis …

Aluminum is a ubiquitously abundant nonessential element. Aluminum has been associated
with neurodegenerative diseases such as Alzheimer's disease (AD), amyotrophic lateral …

The proposition that environmental agents, such as diet, aluminum, and viruses, are as
important as genetic factors in the etiology of Alzheimer's disease (AD) was advanced by the …

Proton MR spectroscopy (MRS) studies have found both decreased N-acetylaspartate (NAA)
and increased myo-inositol in the occipital, temporal, parietal, and frontal regions of patients …