Protoplast Isolation and Shoot Regeneration from Protoplast-Derived Callus of Petunia hybrida Cv. Mirage Rose
Despite the increasing use of protoplasts in plant biotechnology research, shoot
regeneration from protoplasts remains challenging. In this study, we investigated the factors …
regeneration from protoplasts remains challenging. In this study, we investigated the factors …
Acute lipopolysaccharide (LPS)-induced cell membrane hyperpolarization is independent of voltage gated and calcium activated potassium channels
S McCubbin, A Meade, DA Harrison… - … and Physiology Part C …, 2024 - Elsevier
The gram-negative toxin lipopolysaccharides (LPS) are known to trigger inflammatory
cytokines in mammals, which can result in pathological responses. Upon treatment of …
cytokines in mammals, which can result in pathological responses. Upon treatment of …
Hyperpolarization Induced by Lipopolysaccharides but Not by Chloroform Is Inhibited by Doxapram, an Inhibitor of Two-P-Domain K+ Channel (K2P)
Bacterial septicemia is commonly induced by Gram-negative bacteria. The immune
response is triggered in part by the secretion of bacterial endotoxin lipopolysaccharide …
response is triggered in part by the secretion of bacterial endotoxin lipopolysaccharide …
The effects of doxapram blocking the response of gram-negative bacterial toxin (LPS) at glutamatergic synapses
KE Brock, RL Cooper - Biology, 2023 - mdpi.com
Simple Summary The actions of bacterial toxin lipopolysaccharides (LPS) can lead to the
development of illness in humans and animals by triggering an immune system response …
development of illness in humans and animals by triggering an immune system response …
Bacterial lipopolysaccharide hyperpolarizes the membrane potential and is antagonized by the K2p channel blocker doxapram
RM Vacassenno, CN Haddad, RL Cooper - Comparative Biochemistry and …, 2023 - Elsevier
Exposure of Drosophila skeletal muscle to bacterial lipopolysaccharides (LPS) rapidly and
transiently hyperpolarizes membrane potential. However, the mechanism responsible for …
transiently hyperpolarizes membrane potential. However, the mechanism responsible for …
Rapid and Direct Action of Lipopolysaccharide (LPS) on Skeletal Muscle of Larval Drosophila
R Potter, A Meade, S Potter, RL Cooper - Biology, 2021 - mdpi.com
Simple Summary The direct action of a toxin, lipopolysaccharide, which is released from
bacteria, on tissues is still not well understood. Skeletal muscle exposed to …
bacteria, on tissues is still not well understood. Skeletal muscle exposed to …
Bacterial endotoxin lipopolysaccharide enhances synaptic transmission at low-output glutamatergic synapses
The endotoxin lipopolysaccharides (LPS), secreted from gram-negative bacteria, has direct
effects on synaptic transmission independent of systemic secondary cytokine responses …
effects on synaptic transmission independent of systemic secondary cytokine responses …
The effects of Gram-positive and Gram-negative bacterial toxins (LTA & LPS) on cardiac function in Drosophila melanogaster larvae
KE Brock, ER Elliott, MO Abul-Khoudoud… - Journal of Insect …, 2023 - Elsevier
The effects of Gram negative and positive bacterial sepsis depend on the type of toxins
released, such as lipopolysaccharides (LPS) or lipoteichoic acid (LTA). Previous studies …
released, such as lipopolysaccharides (LPS) or lipoteichoic acid (LTA). Previous studies …
Mutations of γCOP Gene Disturb Drosophila melanogaster Innate Immune Response to Pseudomonas aeruginosa
Drosophila melanogaster (the fruit fly) is a valuable experimental platform for modeling host–
pathogen interactions. It is also commonly used to define innate immunity pathways and to …
pathogen interactions. It is also commonly used to define innate immunity pathways and to …
Fluoxetine antagonizes the acute response of LPS: Blocks K2P channels
ER Elliott, RL Cooper - Comparative Biochemistry and Physiology Part C …, 2025 - Elsevier
The channels responsible for maintaining resting membrane potential are known as K2P
(two-P-domain K+ subunit) channels, a subset of which are known to be blocked by …
(two-P-domain K+ subunit) channels, a subset of which are known to be blocked by …