Updated assessment of the prevalence, spectrum and case definition of autoimmune disease
SM Hayter, MC Cook - Autoimmunity reviews, 2012 - Elsevier
Autoimmune diseases are heterogeneous with regard to prevalence, manifestations, and
pathogenesis. The classification of autoimmune diseases has varied over time. Here, we …
pathogenesis. The classification of autoimmune diseases has varied over time. Here, we …
The role of endothelial cells in the vasculopathy of systemic sclerosis: a systematic review
Y Mostmans, M Cutolo, C Giddelo, S Decuman… - Autoimmunity …, 2017 - Elsevier
Abstract Introduction Systemic sclerosis (SSc) is an autoimmune connective tissue disorder
characterized by fibroproliferative vasculopathy, immunological abnormalities and …
characterized by fibroproliferative vasculopathy, immunological abnormalities and …
Autoantibodies in systemic sclerosis
S Mehra, J Walker, K Patterson, MJ Fritzler - Autoimmunity reviews, 2013 - Elsevier
Autoantibodies directed against a variety of nuclear, cytoplasmic and extracellular
autoantigens are a serological hallmark of systemic sclerosis. This review provides an …
autoantigens are a serological hallmark of systemic sclerosis. This review provides an …
Type I interferons: crucial participants in disease amplification in autoimmunity
JC Hall, A Rosen - Nature Reviews Rheumatology, 2010 - nature.com
A significant body of data implicates the type I interferon (IFN) pathway in the pathogenesis
of autoimmune rheumatic diseases. In these disorders, a self-reinforcing cycle of IFN …
of autoimmune rheumatic diseases. In these disorders, a self-reinforcing cycle of IFN …
Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccination
N Jounai, K Kobiyama, F Takeshita… - Frontiers in cellular and …, 2013 - frontiersin.org
All mammalian cells are equipped with large numbers of sensors for protection from various
sorts of invaders, who, in turn, are equipped with molecules containing pathogen-associated …
sorts of invaders, who, in turn, are equipped with molecules containing pathogen-associated …
IFI16 phase separation via multi-phosphorylation drives innate immune signaling
The interferon inducible protein 16 (IFI16) is a prominent sensor of nuclear pathogenic DNA,
initiating innate immune signaling and suppressing viral transcription. However, little is …
initiating innate immune signaling and suppressing viral transcription. However, little is …
Novel autoantibodies in Sjögren's syndrome: a comprehensive review
E Martín-Nares, G Hernández-Molina - Autoimmunity reviews, 2019 - Elsevier
Sjögren's syndrome is a systemic autoimmune disease characterized by immune-mediated
injury of exocrine glands, as well as a diverse array of extraglandular manifestations. B cell …
injury of exocrine glands, as well as a diverse array of extraglandular manifestations. B cell …
Renal interferon-inducible protein 16 expression is associated with disease activity and prognosis in lupus nephritis
X Wang, S Fu, J Yu, F Ma, L Zhang, J Wang… - Arthritis Research & …, 2023 - Springer
Background Lupus nephritis (LN) is one of the most severe complications of systemic lupus
erythematosus (SLE). However, the current management of LN remains unsatisfactory due …
erythematosus (SLE). However, the current management of LN remains unsatisfactory due …
Interferon-inducible Ifi200-family genes in systemic lupus erythematosus
D Choubey, R Panchanathan - Immunology letters, 2008 - Elsevier
Systemic lupus erythematosus (SLE) is the prototype of complex autoimmune diseases.
Studies have suggested that genetic, hormonal, and environmental factors contribute to the …
Studies have suggested that genetic, hormonal, and environmental factors contribute to the …
Roles of inflammasomes in inflammatory kidney diseases
J Fan, K Xie, L Wang, N Zheng… - Mediators of Inflammation, 2019 - Wiley Online Library
The immune system has a central role in eliminating detrimental factors, by frequently
launching inflammatory responses towards pathogen infection and inner danger signal …
launching inflammatory responses towards pathogen infection and inner danger signal …