Intrinsically Disordered Proteins (IDPs) and Regions (IDRs) exist widely. Although without
well-defined structures, they participate in many important biological processes. In addition …

Predicting protein interactions in the cellular environment still remains a challenge in the
AlphaFold era. Protein interactions, similarly to their structures, sample a continuum from …

AlphaFold2 (AF2) has created a breakthrough in biology by providing three-dimensional
structure models for whole-proteome sequences, with unprecedented levels of accuracy. In …

An increasing number of protein interaction domains and their targets are being found to be
intrinsically disordered proteins (IDPs). The corresponding target recognition mechanisms …

To reduce the environmental pollution caused by organic solvents and improve the
extraction efficiency, a range of imidazolium-based ionic liquid (IL) combinations of [Omim]+ …

Intrinsically disordered proteins (IDPs) exploit their plasticity to deploy a rich panoply of soft
interactions and binding phenomena. Advances in tailoring molecular simulations for IDPs …

Intrinsically disordered proteins (IDPs) lack a well-defined tertiary structure but are essential
players in various biological processes. Their ability to undergo a disorder-to-order transition …

GV-971 (sodium oligomannate) is a China Food and Drug Administration (CFDA)-approved
drug for treating Alzheimer's disease, and it could inhibit Aβ fibril formation in vitro and in …

Leukocyte adhesion deficiency-1 (LAD-1) disorder is a severe immunodeficiency syndrome
caused by deficiency or mutation of β2 integrin. The phosphorylation on threonine 758 of β2 …

The centromere is epigenetically marked by a histone H3 variant-CENP-A. The budding
yeast CENP-A called Cse4, consists of an unusually long N-terminus that is known to be …