The Candida pathogenic species complex
Candida species are the most common causes of fungal infection. Approximately 90% of
infections are caused by five species: Candida albicans, Candida glabrata, Candida …
infections are caused by five species: Candida albicans, Candida glabrata, Candida …
[HTML][HTML] Drug resistance and novel therapeutic approaches in invasive candidiasis
SE Murphy, T Bicanic - Frontiers in cellular and infection microbiology, 2021 - frontiersin.org
Candida species are the leading cause of invasive fungal infections worldwide and are
associated with acute mortality rates of~ 50%. Mortality rates are further augmented in the …
associated with acute mortality rates of~ 50%. Mortality rates are further augmented in the …
Components of the calcium-calcineurin signaling pathway in fungal cells and their potential as antifungal targets
S Liu, Y Hou, W Liu, C Lu, W Wang, S Sun - Eukaryotic cell, 2015 - Am Soc Microbiol
In recent years, the emergence of fungal resistance has become frequent, partly due to the
widespread clinical use of fluconazole, which is minimally toxic and effective in the …
widespread clinical use of fluconazole, which is minimally toxic and effective in the …
Calcineurin Plays Key Roles in the Dimorphic Transition and Virulence of the Human Pathogenic Zygomycete Mucor circinelloides
Many pathogenic fungi are dimorphic and switch between yeast and filamentous states. This
switch alters host-microbe interactions and is critical for pathogenicity. However, in …
switch alters host-microbe interactions and is critical for pathogenicity. However, in …
Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach
Increases in the incidence and mortality due to the major invasive fungal infections such as
aspergillosis, candidiasis and cryptococcosis caused by the species of Aspergillus, Candida …
aspergillosis, candidiasis and cryptococcosis caused by the species of Aspergillus, Candida …
Calcineurin-Crz1 signaling in lower eukaryotes
S Thewes - Eukaryotic cell, 2014 - Am Soc Microbiol
Calcium ions are ubiquitous intracellular messengers. An increase in the cytosolic Ca2+
concentration activates many proteins, including calmodulin and the Ca2+/calmodulin …
concentration activates many proteins, including calmodulin and the Ca2+/calmodulin …
Combination of fluconazole with non-antifungal agents: a promising approach to cope with resistant Candida albicans infections and insight into new antifungal agent …
S Liu, Y Hou, X Chen, Y Gao, H Li, S Sun - International journal of …, 2014 - Elsevier
The past decades have witnessed a dramatic increase in invasive fungal infections,
especially candidiasis. Despite the development of more effective new antifungal agents …
especially candidiasis. Despite the development of more effective new antifungal agents …
Oropharyngeal candidosis in HIV-infected patients—an update
Oropharyngeal candidosis (OPC) is an opportunistic fungal infection that is commonly found
in HIV-infected patients, even in the twenty-first century. Candida albicans is the main …
in HIV-infected patients, even in the twenty-first century. Candida albicans is the main …
Candida lusitaniae: Biology, Pathogenicity, Virulence Factors, Diagnosis, and Treatment
DF Mendoza-Reyes, M Gómez-Gaviria… - Infection and Drug …, 2022 - Taylor & Francis
The incidence of fungal infections is increasing at an alarming rate and has posed a great
challenge for science in recent years. The rise in these infections has been related to the …
challenge for science in recent years. The rise in these infections has been related to the …
Synergistic Effect of Fluconazole and Calcium Channel Blockers against Resistant Candida albicans
S Liu, L Yue, W Gu, X Li, L Zhang, S Sun - PloS one, 2016 - journals.plos.org
Candidiasis has increased significantly recently that threatens patients with low immunity.
However, the number of antifungal drugs on the market is limited in comparison to the …
However, the number of antifungal drugs on the market is limited in comparison to the …