An update on antifungal resistance in dermatophytosis

AK Gupta, A Mann, S Polla Ravi… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction The reports of resistance to antifungal agents used for treating onychomycosis
and other superficial fungal infections are increasing. This rise in antifungal resistance …

Antifungal resistance in dermatophytes – review of the epidemiology, diagnostic challenges and treatment strategies for managing Trichophyton indotineae infections

AK Gupta, T Wang, A Mann, S Polla Ravi… - Expert Review of Anti …, 2024 - Taylor & Francis
Introduction There is an increasing number of reports of Trichophyton indotineae infections.
This species is usually poorly responsive to terbinafine. Areas covered A literature search …

Two different types of tandem sequences mediate the overexpression of TinCYP51B in azole-resistant Trichophyton indotineae

T Yamada, M Maeda, H Nagai, K Salamin… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
Trichophyton indotineae is an emerging dermatophyte that causes severe tinea corporis and
tinea cruris. Numerous cases of terbinafine-and azole-recalcitrant T. indotineae-related …

Trichophyton indotineae and other terbinafine-resistant dermatophytes in North America

SR Lockhart, DJ Smith, JAW Gold - Journal of Clinical …, 2023 - Am Soc Microbiol
Dermatophyte infections (aka ringworm, tinea) affect an estimated 20%–25% of the world's
population. In North America, most dermatophytoses are caused by Trichophyton rubrum or …

Development of an agar-based screening method for terbinafine, itraconazole, and amorolfine susceptibility testing of Trichophyton spp.

M Siopi, I Efstathiou, MC Arendrup… - Journal of Clinical …, 2024 - Am Soc Microbiol
Resistance in dermatophytes is an emerging global public health issue. We, therefore,
developed an agar-based method for screening Trichophyton spp. susceptibility to …

Efinaconazole 10% solution: a comprehensive review of its use in the treatment of onychomycosis

AK Gupta, A Mann, S Polla Ravi, T Wang… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Onychomycosis is an infection of the nail bed and the nail plate. While oral
antifungals are first-line for moderate-to-severe onychomycosis, topical efinaconazole 10 …

High Prevalence of Terbinafine Resistance Among Trichophyton mentagrophytes/T. interdigitale Species Complex, a Cross-Sectional Study from 2021 to 2022 in …

I Haghani, M Babaie, A Hoseinnejad… - Mycopathologia, 2024 - Springer
Abstract Treatment-resistant dermatophytosis caused by the members of the Trichophyton
mentagrophytes/Trichophyton interdigitale species group (TMTISG) is increasing worldwide …

[HTML][HTML] Antifungal Resistance on the Rise

M Monod, G Blanchard, E Guenova - Journal of Investigative Dermatology, 2023 - Elsevier
Terbinafine is a major antifungal compound for the treatment of dermatophyte
onychomycosis. Drug resistance resulting from mutations in the enzyme targeted by …

Patient Characteristics, Diagnostic Testing Utilization, and Antifungal Prescribing Pattern for Onychomycosis in the USA: A Cohort Study Using DataDerm, 2016–2022

AK Gupta, T Wang, AN Tran - Skin Appendage Disorders, 2024 - karger.com
Introduction: Onychomycosis is a complex nail disease that is commonly seen in daily
practice. Methods: Electronic health records of clinically diagnosed onychomycosis patients …

[PDF][PDF] Autochthonous Trichophyton rubrum terbinafine resistance in France: Assessment of antifungal susceptibility tests

A Moreno-Sabater, C Cordier… - Clinical …, 2024 - hal.sorbonne-universite.fr
Terbinafine resistance is now a serious issue in dermatophytosis treatment due to the 43
worldwide expansion of Trichophyton indotineae. Incidence of terbinafine treatment failure is …