Adult skeletal muscle in mammals is a stable tissue under normal circumstances but has
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …

Although senescence was originally described as an in vitro acquired cellular characteristic,
it was recently recognized that senescence is physiologically and pathologically involved in …

Background Although progenitor cells have been described in distinct anatomical regions of
the lung, description of resident stem cells has remained elusive. Methods Surgical lung …

With the explosion of knowledge from molecular biology and the burgeoning interest in
generating or regenerating tissues or organs through various bioengineering or stem cell …

Platinum-based chemotherapy is the first-line treatment for non–small cell lung cancer, but
recurrence occurs in most patients. Recent evidence suggests that CD133+ cells are the …

Denervation changes in skeletal muscle (atrophy; alterations of myofibrillar expression,
muscle membrane electrical properties, ACh sensitivity and excitation–contraction coupling …

Neuromuscular junction (NMJ) formation, occurring between motoneurons and skeletal
muscle, is a complex multistep process involving a variety of signaling molecules and …

Fibrotic disorders are typified by excessive connective tissue and extracellular matrix (ECM)
deposition that precludes normal healing processes of different tissues. Connective tissue …

The peripheral nervous system has the intrinsic capacity to regenerate but the reinnervation
of muscles is often suboptimal and results in limited recovery of function. Injuries to nerves …

Obesity and its related cluster of pathophysiologic conditions including insulin resistance,
glucose intolerance, dyslipidemia, and hypertension are recognized as growing threats to …