The hand endows us with unparalleled precision and versatility in our interactions with
objects, from mundane activities such as grasping to extraordinary ones such as virtuoso …

One of the great strengths of the mouse model is the wide array of genetic tools that have
been developed. Striking examples include methods for directed modification of the …

Advances in our understanding of sensory-motor integration suggest a unique role of the
frontal lobe circuits in cognition and behaviour. Long-range afferent connections convey …

The two visual systems hypothesis suggests processing of visual information into two distinct
routes in the brain: a dorsal stream for the control of actions and a ventral stream for the …

Eighty years ago, Penfield and Boldrey introduced the homunculus in a paper published in
Brain. In a reappraisal of the iconic aide-mémoire, Marco Catani reanalyses the original …

Stroke is a leading cause of disability. While neurotechnology has shown promise for
improving upper limb recovery after stroke, efficacy in clinical trials has been variable. Our …

Transcranial magnetic stimulation (TMS) methods such as cortico-cortical paired associative
stimulation (ccPAS) can increase the strength of functional connectivity between ventral …

Posterior parietal cortex (PPC) plays an important role in the planning and control of goal-
directed action. Single-unit studies in monkeys have identified reach-specific areas in the …

Grasping requires translating object geometries into appropriate hand shapes. How the
brain computes these transformations is currently unclear. We investigated three key areas …

Cortico-cortical paired associative stimulation (ccPAS) is an effective transcranial magnetic
stimulation (TMS) method for inducing associative plasticity between interconnected brain …