Circadian clock organization in the retina: From clock components to rod and cone pathways and visual function
Abstract Circadian (24-h) clocks are cell-autonomous biological oscillators that orchestrate
many aspects of our physiology on a daily basis. Numerous circadian rhythms in …
many aspects of our physiology on a daily basis. Numerous circadian rhythms in …
Artificial intelligence techniques for retinal prostheses: A comprehensive review and future direction
Objective. Retinal prostheses are promising devices to restore vision for patients with severe
age-related macular degeneration or retinitis pigmentosa disease. The visual processing …
age-related macular degeneration or retinitis pigmentosa disease. The visual processing …
[HTML][HTML] Divergent outer retinal circuits drive image and non-image visual behaviors
Image-and non-image-forming vision are essential for animal behavior. Here we use
genetically modified mouse lines to examine retinal circuits driving image-and non-image …
genetically modified mouse lines to examine retinal circuits driving image-and non-image …
[HTML][HTML] Layers of inhibitory networks shape receptive field properties of AII amacrine cells
In the retina, rod and cone pathways mediate visual signals over a billion-fold range in
luminance. AII (" A-two") amacrine cells (ACs) receive signals from both pathways via …
luminance. AII (" A-two") amacrine cells (ACs) receive signals from both pathways via …
Analysis of rod/cone gap junctions from the reconstruction of mouse photoreceptor terminals
M Ishibashi, J Keung, CW Morgans, SA Aicher… - Elife, 2022 - elifesciences.org
Electrical coupling, mediated by gap junctions, contributes to signal averaging,
synchronization, and noise reduction in neuronal circuits. In addition, gap junctions may also …
synchronization, and noise reduction in neuronal circuits. In addition, gap junctions may also …
[HTML][HTML] Electrical synaptic transmission requires a postsynaptic scaffolding protein
AM Lasseigne, FA Echeverry, S Ijaz, JC Michel… - Elife, 2021 - elifesciences.org
Electrical synaptic transmission relies on neuronal gap junctions containing channels
constructed by Connexins. While at chemical synapses neurotransmitter-gated ion channels …
constructed by Connexins. While at chemical synapses neurotransmitter-gated ion channels …
[HTML][HTML] Development and maintenance of vision's first synapse
Synapses in the outer retina are the first information relay points in vision. Here,
photoreceptors form synapses onto two types of interneurons, bipolar cells and horizontal …
photoreceptors form synapses onto two types of interneurons, bipolar cells and horizontal …
[HTML][HTML] Function and plasticity of electrical synapses in the mammalian brain: role of non-junctional mechanisms
Simple Summary Relevant brain functions, such as perception, organization of behavior,
and cognitive processes, are the outcome of information processing by neural circuits …
and cognitive processes, are the outcome of information processing by neural circuits …
[HTML][HTML] Loss of Gap Junction Delta-2 (GJD2) gene orthologs leads to refractive error in zebrafish
WH Quint, KCD Tadema, E de Vrieze… - Communications …, 2021 - nature.com
Myopia is the most common developmental disorder of juvenile eyes, and it has become an
increasing cause of severe visual impairment. The GJD2 locus has been consistently …
increasing cause of severe visual impairment. The GJD2 locus has been consistently …
Nanotechnology for vision restoration
Degenerative retinal dystrophies, such as retinitis pigmentosa and age-related macular
degeneration, cause the progressive loss of retinal photoreceptors, which leads to …
degeneration, cause the progressive loss of retinal photoreceptors, which leads to …