Cuproptosis and cuproptosis–related genes in rheumatoid arthritis: Implication, prospects, and perspectives
Rheumatoid arthritis (RA) is an autoimmune disease that severely affects patients' physical
and mental health, leading to chronic synovitis and destruction of bone joints. Although …
and mental health, leading to chronic synovitis and destruction of bone joints. Although …
Ferroptosis and autoimmune diseases
B Lai, CH Wu, CY Wu, SF Luo, JH Lai - Frontiers in Immunology, 2022 - frontiersin.org
Adequate control of autoimmune diseases with an unclear etiology resulting from
autoreactivation of the immune system remains a major challenge. One of the factors that …
autoreactivation of the immune system remains a major challenge. One of the factors that …
Inflammatory response to regulated cell death in gout and its functional implications
J Zhao, K Wei, P Jiang, C Chang, L Xu, L Xu… - Frontiers in …, 2022 - frontiersin.org
Gout, a chronic inflammatory arthritis disease, is characterized by hyperuricemia and caused
by interactions between genetic, epigenetic, and metabolic factors. Acute gout symptoms are …
by interactions between genetic, epigenetic, and metabolic factors. Acute gout symptoms are …
Role of reactive oxygen species and mitochondrial damage in rheumatoid arthritis and targeted drugs
W Jing, C Liu, C Su, L Liu, P Chen, X Li… - Frontiers in …, 2023 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial
inflammation, pannus formation, and bone and cartilage damage. It has a high disability …
inflammation, pannus formation, and bone and cartilage damage. It has a high disability …
Ferroptosis, necroptosis, and pyroptosis in the occurrence and development of ovarian cancer
C Zhang, N Liu - Frontiers in immunology, 2022 - frontiersin.org
Ovarian cancer (OC) is one of the most common malignancies that causes death in women
and is a heterogeneous disease with complex molecular and genetic changes. Because of …
and is a heterogeneous disease with complex molecular and genetic changes. Because of …
Natural medicines of targeted rheumatoid arthritis and its action mechanism
X Liu, Z Wang, H Qian, W Tao, Y Zhang, C Hu… - Frontiers in …, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease involving joints, with clinical
manifestations of joint inflammation, bone damage and cartilage destruction, joint …
manifestations of joint inflammation, bone damage and cartilage destruction, joint …
The emerging role of pyroptosis in pediatric cancers: from mechanism to therapy
H Wang, X Zhou, C Li, S Yan, C Feng, J He… - Journal of hematology & …, 2022 - Springer
Pediatric cancers are the driving cause of death for children and adolescents. Due to safety
requirements and considerations, treatment strategies and drugs for pediatric cancers have …
requirements and considerations, treatment strategies and drugs for pediatric cancers have …
Pyroptosis by NLRP3/caspase‐1/gasdermin‐D pathway in synovial tissues of rheumatoid arthritis patients
X Zhang, Q Wang, G Cao, M Luo… - Journal of Cellular and …, 2023 - Wiley Online Library
We investigated the potential involvement of pyroptosis, a proinflammatory form of regulated
cell death, in rheumatoid arthritis (RA). Synovial fluid, synovial tissues and/or serum were …
cell death, in rheumatoid arthritis (RA). Synovial fluid, synovial tissues and/or serum were …
[HTML][HTML] Celastrol inhibits rheumatoid arthritis by inducing autophagy via inhibition of the PI3K/AKT/mTOR signaling pathway
J Yang, J Liu, J Li, M Jing, L Zhang, M Sun… - International …, 2022 - Elsevier
Objective Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder of the
synovial joints. Celastrol (Cel) is a quinone-methylated triterpenoid extracted from …
synovial joints. Celastrol (Cel) is a quinone-methylated triterpenoid extracted from …
Mitochondrial dysfunction and oxidative stress in rheumatoid arthritis
MJ López-Armada, JA Fernández-Rodríguez… - Antioxidants, 2022 - mdpi.com
Control of excessive mitochondrial oxidative stress could provide new targets for both
preventive and therapeutic interventions in the treatment of chronic inflammation or any …
preventive and therapeutic interventions in the treatment of chronic inflammation or any …