Heterogeneity and diversity of striatal GABAergic interneurons: update 2018

JM Tepper, T Koós, O Ibanez-Sandoval… - Frontiers in …, 2018 - frontiersin.org
Our original review,“Heterogeneity and Diversity of Striatal GABAergic Interneurons,” to
which this is an invited update, was published in December, 2010 in Frontiers is …

Structural and functional organization of the midline and intralaminar nuclei of the thalamus

RP Vertes, SB Linley, AKP Rojas - Frontiers in Behavioral …, 2022 - frontiersin.org
The midline and intralaminar nuclei of the thalamus form a major part of the “limbic
thalamus;” that is, thalamic structures anatomically and functionally linked with the limbic …

The functional organization of cortical and thalamic inputs onto five types of striatal neurons is determined by source and target cell identities

Y Johansson, G Silberberg - Cell reports, 2020 - cell.com
To understand striatal function, it is essential to know the functional organization of the
numerous inputs targeting the diverse population of striatal neurons. Using optogenetics, we …

Differential inputs to striatal cholinergic and parvalbumin interneurons imply functional distinctions

JR Klug, MD Engelhardt, CN Cadman, H Li, JB Smith… - elife, 2018 - elifesciences.org
Striatal cholinergic (ChAT) and parvalbumin (PV) interneurons exert powerful influences on
striatal function in health and disease, yet little is known about the organization of their …

Excitatory extrinsic afferents to striatal interneurons and interactions with striatal microcircuitry

M Assous, JM Tepper - European Journal of Neuroscience, 2019 - Wiley Online Library
The striatum constitutes the main input structure of the basal ganglia and receives two major
excitatory glutamatergic inputs, from the cortex and the thalamus. Excitatory cortico‐and …

Disrupted striatal neuron inputs and outputs in Huntington's disease

A Reiner, YP Deng - CNS neuroscience & therapeutics, 2018 - Wiley Online Library
Huntington's disease (HD) is a hereditary progressive neurodegenerative disorder caused
by a CAG repeat expansion in the gene coding for the protein huntingtin, resulting in a …

[HTML][HTML] Connectivity of the corticostriatal and thalamostriatal systems in normal and parkinsonian states: an update

AC Martel, A Galvan - Neurobiology of disease, 2022 - Elsevier
The striatum receives abundant glutamatergic afferents from the cortex and thalamus. These
inputs play a major role in the functions of the striatal neurons in normal conditions, and are …

Synaptic determinants of cholinergic interneurons hyperactivity during parkinsonism

M Padilla-Orozco, M Duhne… - Frontiers in Synaptic …, 2022 - frontiersin.org
Parkinson's disease is a neurodegenerative ailment generated by the loss of dopamine in
the basal ganglia, mainly in the striatum. The disease courses with increased striatal levels …

Role of M4‐receptor cholinergic signaling in direct pathway striatal projection neurons during dopamine depletion

VH Avilés‐Rosas, EA Rendón‐Ochoa… - Synapse, 2024 - Wiley Online Library
Direct pathway striatal projection neurons (dSPNs) are characterized by the expression of
dopamine (DA) class 1 receptors (D1R), as well as cholinergic muscarinic M1 and M4 …

Micropopulation mapping of the mouse parafascicular nucleus connections reveals diverse input–output motifs

E Gonzalo-Martín, C Alonso-Martínez… - Frontiers in …, 2024 - frontiersin.org
Introduction In primates, including humans, the centromedian/parafascicular (CM-Pf)
complex is a key thalamic node of the basal ganglia system. Deep brain stimulation in CM-Pf …