Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …

Kidney-targeted nanoparticles have become of recent interest due to their potential to
deliver drugs directly to diseased tissue, decrease off-target adverse effects, and increase …

The ubiquitous presence of microplastics (MPs) and their health effects is a recent scientific
topic. However, the investigation of MPs in human/biological matrices has several limitations …

Nano-and micro-plastic (NMP) pollution has emerged as a global issue; however, uptake in
the blood is controversial. Also, there is no evidence that NMPs are excreted via urine. This …

Nanoparticle (NP) stiffness has been shown to significantly impact circulation time and
biodistribution in anticancer drug delivery. In particular, the relationship between particle …

In recent years, several publications reported that nanoparticles larger than the kidney
filtration threshold were found intact in the urine after being injected into laboratory mice …

Insufficient data on nano-and microplastics (NMP) hinder robust evaluation of their potential
health risks. Methodological disparities and the absence of established toxicity thresholds …

Most nanomedicines require efficient in vivo delivery to elicit meaningful diagnostic and
therapeutic effects. However, en route to their intended tissues, systemically administered …

Kidney disease management and treatment are currently causing a substantial global
burden. The kidneys are the most important organs in the human urinary system, selectively …

Kidney disease affects more than 10% of the global population and is associated with
considerable morbidity and mortality, highlighting a need for new therapeutic options …