[HTML][HTML] Lights and shadows on the therapeutic use of antimicrobial peptides
D Bellotti, M Remelli - Molecules, 2022 - mdpi.com
The emergence of antimicrobial-resistant infections is still a major concern for public health
worldwide. The number of pathogenic microorganisms capable of resisting common …
worldwide. The number of pathogenic microorganisms capable of resisting common …
[HTML][HTML] Molecular and biological properties of snakins: the foremost cysteine-rich plant host defense peptides
Plant host defense peptides (HDPs), also known as antimicrobial peptides (AMPs), are
regarded as one of the most prevalent barriers elaborated by plants to combat various …
regarded as one of the most prevalent barriers elaborated by plants to combat various …
[HTML][HTML] From oncolytic peptides to oncolytic polymers: A new paradigm for oncotherapy
H Liu, W Shen, W Liu, Z Yang, D Yin, C Xiao - Bioactive Materials, 2024 - Elsevier
Traditional cancer therapy methods, especially those directed against specific intracellular
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …
Antimicrobial peptides as potential therapeutics for breast cancer
Breast cancer is the most common and deadliest cancer in women worldwide. Although
notable advances have been achieved in the treatment of breast cancer, the overall survival …
notable advances have been achieved in the treatment of breast cancer, the overall survival …
[HTML][HTML] The effect of LL37 antimicrobial peptide on FOXE1 and lncRNA PTCSC 2 genes expression in colorectal cancer (CRC) and normal cells
MN Al-Darraji, S َAbdalkareem Jasim… - Asian Pacific journal …, 2022 - ncbi.nlm.nih.gov
Objective: As an innate immune system component, antimicrobial peptides (AMPs) exert
various effects, such as anticancer properties. This study aimed to evaluate the LL37 AMP …
various effects, such as anticancer properties. This study aimed to evaluate the LL37 AMP …
[HTML][HTML] Small activating RNAs: towards the development of new therapeutic agents and clinical treatments
Small double-strand RNA (dsRNA) molecules can activate endogenous genes via an RNA-
based promoter targeting mechanism. RNA activation (RNAa) is an evolutionarily conserved …
based promoter targeting mechanism. RNA activation (RNAa) is an evolutionarily conserved …
Nisin ZP, an Antimicrobial Peptide, Induces Cell Death and Inhibits Non-Small Cell Lung Cancer (NSCLC) Progression in vitro in 2D and 3D Cell Culture
Lung cancer is the leading cause of cancer deaths globally with most of the reported cases
(> 85%) associated with non-small cell lung cancer (NSCLC). Current therapies have …
(> 85%) associated with non-small cell lung cancer (NSCLC). Current therapies have …
Host defense peptides as immunomodulators: The other side of the coin
EM Martell, M Gonzalez-Garcia, L Ständker… - Peptides, 2021 - Elsevier
Host defense peptides (HDPs) exhibit a broad range of antimicrobial and
immunomodulatory activities. In this sense, both functions are like different sides of the same …
immunomodulatory activities. In this sense, both functions are like different sides of the same …
[HTML][HTML] Autophagy, a critical element in the aging male reproductive disorders and prostate cancer: a therapeutic point of view
Autophagy is a highly conserved, lysosome-dependent biological mechanism involved in
the degradation and recycling of cellular components. There is growing evidence that …
the degradation and recycling of cellular components. There is growing evidence that …
[HTML][HTML] Role of different peptides for cancer immunotherapy
Due to the enormous benefits derived from host immune response, immunotherapy has
been regarded among the most effective methods for defending against cancers …
been regarded among the most effective methods for defending against cancers …