The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …

Colorectal cancer (CRC) is the second most common cancer in women and the third most
common in men. Adenocarcinoma accounts for 90% of CRC cases. There has been …

Aims Sodium-glucose co-transporter 2 (SGLT2) inhibitors improve cardiovascular outcomes
in diverse patient populations, but their mechanism of action requires further study. The aim …

TROP-2 is a glycoprotein first described as a surface marker of trophoblast cells, but
subsequently shown to be increased in many solid cancers, with lower expression in certain …

Breast cancer, specifically metastatic breast, is a leading cause of morbidity and mortality in
women. This is mainly due to relapse and reoccurrence of tumor. The primary reason for …

BACKGROUND. Although aberrant glycosylation is recognized as a hallmark of cancer,
glycosylation in clinical breast cancer (BC) metastasis has not yet been studied. While …

Circulating tumour cells (CTCs) are rare tumour cells found in the circulatory system of
certain cancer patients. The clinical and functional significance of CTCs is still under …

Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein primarily
known to mediate homotypic cell contacts in epithelia tissues. Because EpCAM expression …

Increasing attention has been attracted by exosomes in blood-based diagnosis because
cancer cells release more exosomes in serum than normal cells and these exosomes …

The current view is that breast cancer is a stem cell disease characterized by the existence
of cancer cells with stem-like features and tumor-initiating potential. These cells are made …