Oxidative stress and inflammation generated DNA damage by exposure to air pollution particles

P Møller, PH Danielsen, DG Karottki, K Jantzen… - … research/Reviews in …, 2014 - Elsevier
Generation of oxidatively damaged DNA by particulate matter (PM) is hypothesized to occur
via production of reactive oxygen species (ROS) and inflammation. We investigated this …

The road to malignant cell transformation after particulate matter exposure: from oxidative stress to genotoxicity

M Santibáñez-Andrade… - International journal of …, 2023 - mdpi.com
In cells, oxidative stress is an imbalance between the production/accumulation of oxidants
and the ability of the antioxidant system to detoxify these reactive products. Reactive oxygen …

Oxidative DNA damage and inflammatory responses in cultured human cells and in humans exposed to traffic-related particles

U Vattanasit, P Navasumrit, MB Khadka… - International journal of …, 2014 - Elsevier
Particulate pollution is a major public health concern because epidemiological studies have
demonstrated that exposure to particles is associated with respiratory diseases and lung …

Effects of ambient PM2.5 on pathological injury, inflammation, oxidative stress, metabolic enzyme activity, and expression of c-fos and c-jun in lungs of rats

R Li, X Kou, L Xie, F Cheng, H Geng - Environmental Science and …, 2015 - Springer
Abstract Fine particulate matter (PM 2.5) exposure is associated with morbidity and mortality
induced by respiratory diseases and increases the lung cancer risk. However, the …

Shape-engineered titanium dioxide nanoparticles (TiO2-NPs): cytotoxicity and genotoxicity in bronchial epithelial cells

M Gea, S Bonetta, L Iannarelli, AM Giovannozzi… - Food and Chemical …, 2019 - Elsevier
The aim of this study was to evaluate cytotoxicity (WST-1 assay), LDH release (LDH assay)
and genotoxicity (Comet assay) of three engineered TiO 2-NPs with different shapes …

Gene expression profiling of A549 cells exposed to Milan PM2. 5

M Gualtieri, E Longhin, M Mattioli, P Mantecca… - Toxicology letters, 2012 - Elsevier
BACKGROUND: Particulate matter (PM) has been associated to adverse health effects in
exposed population and DNA damage has been extensively reported in in vitro systems …

Toxicity and endocrine-disrupting potential of PM2. 5: Association with particulate polycyclic aromatic hydrocarbons, phthalate esters, and heavy metals

Q Zhou, J Chen, J Zhang, F Zhou, J Zhao, X Wei… - Environmental …, 2022 - Elsevier
The adverse effects of fine atmospheric particulate matter with aerodynamic diameters of≤
2.5 μm (PM 2.5) are closely associated with particulate chemicals. In this study, PM 2.5 …

Chemical identity and cardiovascular toxicity of hydrophobic organic components in PM2. 5

Z Qi, Y Zhang, ZF Chen, C Yang, Y Song, X Liao… - Ecotoxicology and …, 2020 - Elsevier
Numerous experimental and epidemiological studies have demonstrated that exposure to
PM 2.5 may result in pathogenesis of several major cardiovascular diseases (CVDs), which …

Physical activity, lifestyle factors and oxidative stress in middle age healthy subjects

E Carraro, T Schilirò, F Biorci, V Romanazzi… - International journal of …, 2018 - mdpi.com
Oxidative stress (OS) has been recognized to play a primary role in many acute and chronic
diseases. Environmental and lifestyle factors, such as physical activity and dietary intake are …

Polycyclic aromatic hydrocarbons in the water-SPM-sediment system from the middle reaches of Huai River, China: Distribution, partitioning, origin tracing and …

J Zhang, G Liu, R Wang, H Huang - Environmental Pollution, 2017 - Elsevier
The polycyclic aromatic hydrocarbons (PAHs) concentrations in the water, suspended
particulate matter (SPM) and sediment from the middle reaches of Huai River were analyzed …