Abstract Pakistan, India, Sri Lanka, Bangladesh, Nepal and Bhutan, with their total
population of more than 1,500 million, make up the subcontinent of South Asia. Despite …

Purpose This meta-anlaysis quantitatively assessed an overall independent association
between areca nut chewing and esophageal squamous-cell carcinoma in Asians. Methods …

Aldehyde dehydrogenase 1 (ALDH1) has been considered to be a marker for cancer stem
cells. However, the role of ALDH1 in head and neck squamous cell carcinoma (HNSCC) has …

Oral squamous cell carcinoma (OSCC) has the highest prevalence in head and neck
cancers and is the first and second most common cancer in males and females of Pakistan …

We aimed to assess the risk of oral cancer incidence in a high-risk population, establish a
predictive model for oral cancer among these high-risk individuals, and assess the …

Head and neck squamous cell carcinoma (HNSCC) is a prevalent cancer worldwide. Signal
transducers and activators of transcription 3 (STAT3) signaling is reported to promote tumor …

Head and neck cancer (HNC) is a prevalent cancer worldwide. Let-7 has been shown to
function as a tumour suppressor by regulating multiple oncogenic signalling pathways …

Bmi-1, a member of the Polycomb family of transcriptional repressors, is essential for
maintaining the self-renewal abilities of adult stem cells. Bmi-1 has been demonstrated to …

Background To investigate the socio-economic and demographic determinants of tobacco
use in Rawalpindi, Pakistan. Methods Cross sectional survey of households (population …

Oral cancer (OC) ranked as eleventh malignancy worldwide, with the increasing incidence
among young patients. Limited understanding of complications in cancer progression, its …