Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities

N Rigney, GJ de Vries, A Petrulis, LJ Young - Endocrinology, 2022 - academic.oup.com
Oxytocin and vasopressin are peptide hormones secreted from the pituitary that are well
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …

Rediscovering area CA2: unique properties and functions

SM Dudek, GM Alexander, S Farris - Nature Reviews Neuroscience, 2016 - nature.com
Hippocampal area CA2 has several features that distinguish it from CA1 and CA3, including
a unique gene expression profile, failure to display long-term potentiation and relative …

A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics

T Meira, F Leroy, EW Buss, A Oliva, J Park… - Nature …, 2018 - nature.com
Recent results suggest that social memory requires the dorsal hippocampal CA2 region as
well as a subset of ventral CA1 neurons. However, it is unclear whether dorsal CA2 and …

Oxytocin: the great facilitator of life

HJ Lee, AH Macbeth, JH Pagani, WS Young 3rd - Progress in neurobiology, 2009 - Elsevier
Oxytocin (Oxt) is a nonapeptide hormone best known for its role in lactation and parturition.
Since 1906 when its uterine-contracting properties were described until 50 years later when …

Targeted activation of the hippocampal CA2 area strongly enhances social memory

AS Smith, SK Williams Avram, A Cymerblit-Sabba… - Molecular …, 2016 - nature.com
Social cognition enables individuals to understand others' intentions. Social memory is a
necessary component of this process, for without it, subsequent encounters are devoid of …

Oxytocin and vasopressin: powerful regulators of social behavior

HK Caldwell - The Neuroscientist, 2017 - journals.sagepub.com
For many, the terms oxytocin and vasopressin immediately evoke images of animals
interacting with one another, as both of these neuropeptides have been implicated as being …

Dopamine and oxytocin interactions underlying behaviors: potential contributions to behavioral disorders

TA Baskerville, AJ Douglas - CNS neuroscience & therapeutics, 2010 - Wiley Online Library
Dopamine is an important neuromodulator that exerts widespread effects on the central
nervous system (CNS) function. Disruption in dopaminergic neurotransmission can have …

Social and novel contexts modify hippocampal CA2 representations of space

GM Alexander, S Farris, JR Pirone, C Zheng… - Nature …, 2016 - nature.com
The hippocampus supports a cognitive map of space and is critical for encoding declarative
memory (who, what, when and where). Recent studies have implicated hippocampal …

Developmental perspectives on oxytocin and vasopressin

EAD Hammock - Neuropsychopharmacology, 2015 - nature.com
The related neuropeptides oxytocin and vasopressin are involved in species-typical
behavior, including social recognition behavior, maternal behavior, social bonding …

Role of the vasopressin 1b receptor in rodent aggressive behavior and synaptic plasticity in hippocampal area CA2

JH Pagani, M Zhao, Z Cui, SK Williams Avram… - Molecular …, 2015 - nature.com
The vasopressin 1b receptor (Avpr1b) is critical for social memory and social aggression in
rodents, yet little is known about its specific roles in these behaviors. Some clues to Avpr1b …