The role of early growth response 1 (EGR1) in brain plasticity and neuropsychiatric disorders

F Duclot, M Kabbaj - Frontiers in behavioral neuroscience, 2017 - frontiersin.org
It is now clearly established that complex interactions between genes and environment are
involved in multiple aspects of neuropsychiatric disorders, from determining an individual's …

Molecular mechanisms of early and late LTP

SB Baltaci, R Mogulkoc, AK Baltaci - Neurochemical research, 2019 - Springer
LTP is the most intensively studied cellular model of the memory and generally divided at
least two distinct phases as early and late. E-LTP requires activation of CaMKII that initiates …

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

M Piwecka, P Glažar, LR Hernandez-Miranda… - Science, 2017 - science.org
INTRODUCTION Recently, a special class of RNAs has excited researchers and triggered
hundreds of now-published studies. Known as circular RNAs (circRNAs), these RNAs are …

Transcription factors in long-term memory and synaptic plasticity

CM Alberini - Physiological reviews, 2009 - journals.physiology.org
Transcription is a molecular requisite for long-term synaptic plasticity and long-term memory
formation. Thus, in the last several years, one main interest of molecular neuroscience has …

BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis

CR Bramham, E Messaoudi - Progress in neurobiology, 2005 - Elsevier
Interest in BDNF as an activity-dependent modulator of neuronal structure and function in
the adult brain has intensified in recent years. Localization of BDNF-TrkB to glutamate …

Functional connectivity of multiple brain regions required for the consolidation of social recognition memory

T Tanimizu, JW Kenney, E Okano… - Journal of …, 2017 - Soc Neuroscience
Social recognition memory is an essential and basic component of social behavior that is
used to discriminate familiar and novel animals/humans. Previous studies have shown the …

Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory

T Abel, PV Nguyen, M Barad, TAS Deuel, ER Kandel… - Cell, 1997 - cell.com
To explore the role of protein kinase A (PKA) in the late phase of long-term potentiation (L-
LTP) and memory, we generated transgenic mice that express R (AB), an inhibitory form of …

Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins

T Herdegen, JD Leah - Brain research reviews, 1998 - Elsevier
This article reviews findings up to the end of 1997 about the inducible transcription factors
(ITFs) c-Jun, JunB, JunD, c-Fos, FosB, Fra-1, Fra-2, Krox-20 (Egr-2) and Krox-24 (NGFI-A …

Modulation of cortical excitability by weak direct current stimulation–technical, safety and functional aspects

MA Nitsche, D Liebetanz, A Antal, N Lang… - Supplements to Clinical …, 2003 - Elsevier
Publisher Summary Achieving short-or even long-term neuroplastic functional modifications
of cortical networks through the modulation of activity and excitability of neuronal ensembles …

Experience-dependent gene expression in the rat hippocampus after spatial learning: a comparison of the immediate-early genesArc, c-fos, and zif268

JF Guzowski, B Setlow, EK Wagner… - Journal of …, 2001 - Soc Neuroscience
Neuronal immediate-early gene (IEG) expression is regulated by synaptic activity and plays
an important role in the neuroplastic mechanisms critical to memory consolidation. IEGs can …