AgRP neurons: Regulators of feeding, energy expenditure, and behavior

JD Deem, CL Faber, GJ Morton - The FEBS journal, 2022 - Wiley Online Library
Neurons in the hypothalamic arcuate nucleus (ARC) that express agouti‐related peptide
(AgRP) govern a critical aspect of survival: the drive to eat. Equally important to survival is …

Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ

P Trayhurn, JH Beattie - Proceedings of the Nutrition Society, 2001 - cambridge.org
The traditional role attributed to white adipose tissue is energy storage, fatty acids being
released when fuel is required. The metabolic role of white fat is, however, complex. For …

Methods of activating a melanocortin-4 receptor pathway in obese subjects

LM Kaplan, N Stylopoulos, JL Harris - US Patent 8,476,227, 2013 - Google Patents
Methods and therapeutics are provided for treating metabolic disorders by activation of
melanocortin signaling pathways. Generally, the methods and therapeutics can induce …

Neuroendocrine responses to stress.

RL Matteri, JA Carroll, CJ Dyer - The biology of animal stress …, 2000 - cabidigitallibrary.org
Background Neuroendocrinology can be defined as the study of communication between
the central nervous system and endocrine glands. The term 'neuroendocrine'classically …

[HTML][HTML] Effect of intermittent cold exposure on brown fat activation, obesity, and energy homeostasis in mice

Y Ravussin, C Xiao, O Gavrilova, ML Reitman - PloS one, 2014 - journals.plos.org
Homeotherms have specific mechanisms to maintain a constant core body temperature
despite changes in thermal environment, food supply, and metabolic demand. Brown …

Regulation of body weight and thermogenesis in seasonally acclimatized Brandt's voles (Microtus brandti)

XS Li, DH Wang - Hormones and behavior, 2005 - Elsevier
Seasonal changes in an animal's morphology, physiology, and behavior are considered to
be an adaptive strategy for survival and reproductive success. In the present study, we …

Food or fluid restriction in common laboratory animals: balancing welfare considerations with scientific inquiry

NE Rowland - Comparative medicine, 2007 - ingentaconnect.com
Deprivation or restricted access to either food or fluids is a common research procedure in
laboratory animals. The purpose of the present review is to present and summarize some of …

Increased gene expression of brown fat uncoupling protein (UCP) 1 and skeletal muscle UCP2 and UCP3 in MAC16-induced cancer cachexia

C Bing, M Brown, P King, P Collins, MJ Tisdale… - Cancer research, 2000 - AACR
Weight loss in cancer cachexia is attributable to decreased food intake and/or enhanced
energy expenditure. We investigated the roles of the uncoupling proteins (UCPs) UCP1,-2 …

Seasonal thermogenesis and body mass regulation in plateau pikas (Ochotona curzoniae)

JM Wang, YM Zhang, DH Wang - Oecologia, 2006 - Springer
Abstract Changes in photoperiod, ambient temperature and food availability trigger
seasonal acclimatization in physiology and behavior of many animals. In the present study …

Mechanisms of leptin secretion from white adipocytes

PG Cammisotto, LJ Bukowiecki - American Journal of …, 2002 - journals.physiology.org
The mechanisms regulating leptin secretion were investigated in isolated rat white
adipocytes. Insulin (1–100 nM) linearly stimulated leptin secretion from incubated …