Pulmonary arterial hypertension: pathogenesis and clinical management
Pulmonary hypertension is defined as a resting mean pulmonary artery pressure of 25 mm
Hg or above. This review deals with pulmonary arterial hypertension (PAH), a type of …
Hg or above. This review deals with pulmonary arterial hypertension (PAH), a type of …
Pediatric pulmonary hypertension: guidelines from the American heart association and American thoracic society
Pulmonary hypertension is associated with diverse cardiac, pulmonary, and systemic
diseases in neonates, infants, and older children and contributes to significant morbidity and …
diseases in neonates, infants, and older children and contributes to significant morbidity and …
Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension
Genetic evidence implicates the loss of bone morphogenetic protein type II receptor (BMPR-
II) signaling in the endothelium as an initiating factor in pulmonary arterial hypertension …
II) signaling in the endothelium as an initiating factor in pulmonary arterial hypertension …
Relevant issues in the pathology and pathobiology of pulmonary hypertension
RM Tuder, SL Archer, P Dorfmüller, SC Erzurum… - Journal of the American …, 2013 - jacc.org
Knowledge of the pathobiology of pulmonary hypertension (PH) continues to accelerate.
However, fundamental gaps remain in our understanding of the underlying pathological …
However, fundamental gaps remain in our understanding of the underlying pathological …
Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European …
Thus, the task of writing Guidelines or Expert Consensus documents covers not only the
integration of the most recent research, but also the creation of educational tools and …
integration of the most recent research, but also the creation of educational tools and …
Metabolism in pulmonary hypertension
W Xu, AJ Janocha, SC Erzurum - Annual review of physiology, 2021 - annualreviews.org
Pulmonary arterial hypertension (PAH) is characterized by impaired regulation of pulmonary
hemodynamics and vascular growth. Alterations of metabolism and bioenergetics are …
hemodynamics and vascular growth. Alterations of metabolism and bioenergetics are …
Hypoxic pulmonary vasoconstriction
JT Sylvester, LA Shimoda, PI Aaronson… - Physiological …, 2012 - journals.physiology.org
It has been known for more than 60 years, and suspected for over 100, that alveolar hypoxia
causes pulmonary vasoconstriction by means of mechanisms local to the lung. For the last …
causes pulmonary vasoconstriction by means of mechanisms local to the lung. For the last …
[HTML][HTML] Mechanisms of disease: pulmonary arterial hypertension
RT Schermuly, HA Ghofrani, MR Wilkins… - Nature Reviews …, 2011 - nature.com
Our understanding of, and approach to, pulmonary arterial hypertension has undergone a
paradigm shift in the past decade. Once a condition thought to be dominated by increased …
paradigm shift in the past decade. Once a condition thought to be dominated by increased …
ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation task force on expert consensus …
Writing Committee Members, VV McLaughlin… - Circulation, 2009 - Am Heart Assoc
ACCF/AHA 2009 Expert Consensus Document on Pulmonary Hypertension | Circulation Science
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Updated clinical classification of pulmonary hypertension
G Simonneau, IM Robbins, M Beghetti… - Journal of the American …, 2009 - jacc.org
The aim of a clinical classification of pulmonary hypertension (PH) is to group together
different manifestations of disease sharing similarities in pathophysiologic mechanisms …
different manifestations of disease sharing similarities in pathophysiologic mechanisms …