Biological gene delivery vehicles: beyond viral vectors
Y Seow, MJ Wood - Molecular therapy, 2009 - cell.com
Gene therapy covers a broad spectrum of applications, from gene replacement and
knockdown for genetic or acquired diseases such as cancer, to vaccination, each with …
knockdown for genetic or acquired diseases such as cancer, to vaccination, each with …
Cell-based drug delivery
Drug delivery has been greatly improved over the years by means of chemical and physical
agents that increase bioavailability, improve pharmacokinetic and reduce toxicities. At the …
agents that increase bioavailability, improve pharmacokinetic and reduce toxicities. At the …
Design strategies and applications of circulating cell-mediated drug delivery systems
Drug delivery systems, particularly nanomaterial-based drug delivery systems, possess a
tremendous amount of potential to improve the diagnostic and therapeutic effects of drugs …
tremendous amount of potential to improve the diagnostic and therapeutic effects of drugs …
Drug, enzyme and peptide delivery using erythrocytes as carriers
CG Millan, MLS Marinero, AZ Castaneda… - Journal of controlled …, 2004 - Elsevier
Erythrocytes are potential biocompatible vectors for different bioactive substances, including
drugs. These can be used successfully as biological carriers of drugs, enzymes and …
drugs. These can be used successfully as biological carriers of drugs, enzymes and …
PNA technology
PE Nielsen - Molecular biotechnology, 2004 - Springer
Peptide nucleic acids (PNA) are deoxyribonucleic acid (DNA) mimics with a pseudopeptide
backbone. PNA is an extremely good structural mimic of DNA (or of ribonucleic acid [RNA]) …
backbone. PNA is an extremely good structural mimic of DNA (or of ribonucleic acid [RNA]) …
Applications of carrier erythrocytes in delivery of biopharmaceuticals
M Hamidi, A Zarrin, M Foroozesh… - Journal of controlled …, 2007 - Elsevier
Carrier erythrocytes, resealed erythrocytes loaded by a drug or other therapeutic agents,
have been exploited extensively in recent years for both temporally and spatially controlled …
have been exploited extensively in recent years for both temporally and spatially controlled …
Erythrocyte-based drug delivery
The use of a physiological carrier to deliver therapeutics throughout the body to both
improve their efficacy while minimising inevitable adverse side effects, is an extremely …
improve their efficacy while minimising inevitable adverse side effects, is an extremely …
Immune cell‐mediated biodegradable theranostic nanoparticles for melanoma targeting and drug delivery
Although tremendous efforts have been made on targeted drug delivery systems, current
therapy outcomes still suffer from low circulating time and limited targeting efficiency. The …
therapy outcomes still suffer from low circulating time and limited targeting efficiency. The …
Synthetic and biological vesicular nano-carriers designed for gene delivery
F Soltani, H Parhiz, A Mokhtarzadeh… - Current …, 2015 - ingentaconnect.com
Synthetic and biological vesicular carriers have been recognized as attractive and intelligent
systems for delivery of a verity of bioactive molecules. The importance of such delivery …
systems for delivery of a verity of bioactive molecules. The importance of such delivery …
Nano-engineered immune cells as “guided missiles” for cancer therapy
T Zhang, Z Tai, Z Cui, R Chai, Q Zhu, Z Chen - Journal of Controlled …, 2022 - Elsevier
Immune cells can actively regulate tumors or inflammatory sites and have good
biocompatibility and safety. Currently, they are one of the most promising candidates for …
biocompatibility and safety. Currently, they are one of the most promising candidates for …