Biological gene delivery vehicles: beyond viral vectors

Y Seow, MJ Wood - Molecular therapy, 2009 - cell.com
Gene therapy covers a broad spectrum of applications, from gene replacement and
knockdown for genetic or acquired diseases such as cancer, to vaccination, each with …

Cell-based drug delivery

F Pierigè, S Serafini, L Rossi, M Magnani - Advanced drug delivery reviews, 2008 - Elsevier
Drug delivery has been greatly improved over the years by means of chemical and physical
agents that increase bioavailability, improve pharmacokinetic and reduce toxicities. At the …

Design strategies and applications of circulating cell-mediated drug delivery systems

Y Su, Z Xie, GB Kim, C Dong… - ACS biomaterials science …, 2015 - ACS Publications
Drug delivery systems, particularly nanomaterial-based drug delivery systems, possess a
tremendous amount of potential to improve the diagnostic and therapeutic effects of drugs …

Drug, enzyme and peptide delivery using erythrocytes as carriers

CG Millan, MLS Marinero, AZ Castaneda… - Journal of controlled …, 2004 - Elsevier
Erythrocytes are potential biocompatible vectors for different bioactive substances, including
drugs. These can be used successfully as biological carriers of drugs, enzymes and …

PNA technology

PE Nielsen - Molecular biotechnology, 2004 - Springer
Peptide nucleic acids (PNA) are deoxyribonucleic acid (DNA) mimics with a pseudopeptide
backbone. PNA is an extremely good structural mimic of DNA (or of ribonucleic acid [RNA]) …

Applications of carrier erythrocytes in delivery of biopharmaceuticals

M Hamidi, A Zarrin, M Foroozesh… - Journal of controlled …, 2007 - Elsevier
Carrier erythrocytes, resealed erythrocytes loaded by a drug or other therapeutic agents,
have been exploited extensively in recent years for both temporally and spatially controlled …

Erythrocyte-based drug delivery

L Rossi, S Serafini, F Pierigé, A Antonelli… - Expert opinion on …, 2005 - Taylor & Francis
The use of a physiological carrier to deliver therapeutics throughout the body to both
improve their efficacy while minimising inevitable adverse side effects, is an extremely …

Immune cell‐mediated biodegradable theranostic nanoparticles for melanoma targeting and drug delivery

Z Xie, Y Su, GB Kim, E Selvi, C Ma, V Aragon‐Sanabria… - Small, 2017 - Wiley Online Library
Although tremendous efforts have been made on targeted drug delivery systems, current
therapy outcomes still suffer from low circulating time and limited targeting efficiency. The …

Synthetic and biological vesicular nano-carriers designed for gene delivery

F Soltani, H Parhiz, A Mokhtarzadeh… - Current …, 2015 - ingentaconnect.com
Synthetic and biological vesicular carriers have been recognized as attractive and intelligent
systems for delivery of a verity of bioactive molecules. The importance of such delivery …

Nano-engineered immune cells as “guided missiles” for cancer therapy

T Zhang, Z Tai, Z Cui, R Chai, Q Zhu, Z Chen - Journal of Controlled …, 2022 - Elsevier
Immune cells can actively regulate tumors or inflammatory sites and have good
biocompatibility and safety. Currently, they are one of the most promising candidates for …