Nonalcoholic fatty liver disease is the most prevalent liver disease worldwide, affecting 20%–
25% of the adult population. In 25% of patients, nonalcoholic fatty liver disease progresses …

Liver sinusoidal endothelial cells (LSECs) line the low shear, sinusoidal capillary channels
of the liver and are the most abundant non-parenchymal hepatic cell population. LSECs do …

Non-alcoholic fatty liver disease (NAFLD) and its complications are an expanding health
problem associated with the metabolic syndrome. Liver sinusoidal endothelial cells (LSECs) …

The intestinal microbiota has been linked to the development and prevalence of
steatohepatitis in humans. Interestingly, steatohepatitis is significantly lower in individuals …

Non-alcoholic fatty liver disease (NAFLD) is reaching epidemic proportions, with a global
prevalence of 25% in the adult population. Non-alcoholic steatohepatitis (NASH), which can …

LSECs are a unique population of endothelial cells within the liver and are recognized as
key regulators of liver homeostasis. LSECs also play a key role in liver disease, as …

Abstract Background and Aims Although NASH can lead to severe clinical consequences,
including cirrhosis and hepatocellular carcinoma, no effective treatment is currently …

Non-alcoholic fatty liver disease (NAFLD) and its progressive form non-alcoholic
steatohepatitis (NASH) have emerged as the leading causes of chronic liver disease-related …

Non-alcoholic fatty liver disease (NAFLD) is considered as the hepatic manifestation of
metabolic syndrome, which is characterised by obesity, insulin resistance …

Liver sinusoidal endothelial cells (LSECs) are the gatekeeper cells in the liver, contributing
critical roles in liver physiological and pathological changes. Factors such as dietary …