[HTML][HTML] Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes

A McGuigan, P Kelly, RC Turkington… - World journal of …, 2018 - ncbi.nlm.nih.gov
This review aims to outline the most up-to-date knowledge of pancreatic adenocarcinoma
risk, diagnostics, treatment and outcomes, while identifying gaps that aim to stimulate further …

Cell‐to‐cell communication: microRNAs as hormones

R Bayraktar, K Van Roosbroeck… - Molecular oncology, 2017 - Wiley Online Library
Mammalian cells can release different types of extracellular vesicles (EVs), including
exosomes, microvesicles, and apoptotic bodies. Accumulating evidence suggests that EVs …

Noncoding RNAs in extracellular fluids as cancer biomarkers: the new frontier of liquid biopsies

B Pardini, AA Sabo, G Birolo, GA Calin - Cancers, 2019 - mdpi.com
The last two decades of cancer research have been devoted in two directions:(1)
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …

Early detection of pancreatic cancer: Where are we now and where are we going?

B Zhou, JW Xu, YG Cheng, JY Gao… - … journal of cancer, 2017 - Wiley Online Library
Pancreatic cancer (PC) is one of the most lethal malignancies. Recent studies indicate that
patients with incidentally diagnosed PC have better prognosis than those with symptoms …

miRNA: a diagnostic and therapeutic tool for pancreatic cancer

MI Qadir, A Faheem - Critical Reviews™ in Eukaryotic Gene …, 2017 - dl.begellhouse.com
Pancreatic ductal adenocarcinoma (PDAC) is fatal disease and one of the major causes of
death among cancer patients. Diagnosis of PDAC during the early stages of cancer using …

Potential biomarkers in Lewis negative patients with pancreatic cancer

G Luo, C Liu, M Guo, H Cheng, Y Lu, K Jin, L Liu… - Annals of …, 2017 - journals.lww.com
Objective: To examine potential biomarkers in Lewis negative patients with pancreatic
cancer. Background: Carbohydrate antigen 19–9 (CA19–9) is currently the most important …

Oncogenic microRNAs: key players in malignant transformation

T Frixa, S Donzelli, G Blandino - Cancers, 2015 - mdpi.com
MicroRNAs (miRNAs) represent a class of non-coding RNAs that exert pivotal roles in the
regulation of gene expression at the post-transcriptional level. MiRNAs are involved in many …

Plasma miRNAs in diagnosis and prognosis of pancreatic cancer: A miRNA expression analysis

X Zhou, Z Lu, T Wang, Z Huang, W Zhu, YI Miao - Gene, 2018 - Elsevier
The differential expression of microRNAs (miRNAs) in plasma of pancreatic cancer (PC)
patients may act as a diagnostic biomarker. A four-stage study was performed to identify …

Secretory microRNAs as biomarkers of cancer

K Kai, RL Dittmar, S Sen - Seminars in cell & developmental biology, 2018 - Elsevier
MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression
predominantly by inhibiting transcription and/or promoting degradation of target mRNAs also …

Pancreatic juice exosomal microRNAs as biomarkers for detection of pancreatic ductal adenocarcinoma

S Nakamura, Y Sadakari, T Ohtsuka… - Annals of surgical …, 2019 - Springer
Background Pancreatic ductal adenocarcinoma (PDAC) is a lethal neoplasm because of
difficulties in early detection. Several studies have recently suggested that exosomes may …