Abstract S-nitrosoglutathione reductase (GSNOR), or ADH5, is an enzyme in the alcohol
dehydrogenase (ADH) family. It is unique when compared to other ADH enzymes in that …

Formaldehyde (FA) is a highly reactive substance that is ubiquitous in the environment and
is usually considered as a pollutant. In the human body, FA is a product of various metabolic …

Fanconi anemia (FA) is an inherited bone marrow failure disorder associated with a high
incidence of leukemia and solid tumors. Bone marrow transplantation is currently the only …

S-nitrosylation is a major redox posttranslational modification involved in cell signaling. The
steady state concentration of S-nitrosylated proteins depends on the balance between the …

Innate immunity is the first line of host defense against pathogens. This process is
modulated by multiple antiviral protein modifications, such as phosphorylation and …

S-nitrosylation is a very fundamental post-translational modification of protein and non-
protein thiols due the involvement of it in a variety of cellular processes including …

Subarachnoid hemorrhage (SAH) is a hemorrhagic stroke with a high mortality and disability
rate. Nitric oxide (NO) can promote blood supply through vasodilation, leading to protein S …

Hyperactivation of the NLRP3 inflammasome has been implicated in the pathogenesis of
numerous diseases. However, the precise molecular mechanisms that modulate the …

Neuroblastoma is an embryonal tumor derived from poorly differentiated neural crest cells.
Current research is aimed at identifying the molecular mechanisms that maintain the …

As the population ages, an increasing number of people suffer from age-related cognitive
impairment. However, the mechanisms underlying this process remain unclear. Here, we …