Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria
Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …
accounting for the majority of malaria, and P. vivax being a second important cause …
[HTML][HTML] Invasion of red blood cells by malaria parasites
The malaria parasite is the most important member of the Apicomplexa, a large and highly
successful phylum of intracellular parasites. Invasion of host cells allows apicomplexan …
successful phylum of intracellular parasites. Invasion of host cells allows apicomplexan …
[HTML][HTML] Revealing the Sequence and Resulting Cellular Morphology of Receptor-Ligand Interactions during Plasmodium falciparum Invasion of Erythrocytes
GE Weiss, PR Gilson, T Taechalertpaisarn… - PLoS …, 2015 - journals.plos.org
During blood stage Plasmodium falciparum infection, merozoites invade uninfected
erythrocytes via a complex, multistep process involving a series of distinct receptor-ligand …
erythrocytes via a complex, multistep process involving a series of distinct receptor-ligand …
Immune effector mechanisms in malaria
K Marsh, S Kinyanjui - Parasite immunology, 2006 - Wiley Online Library
That humans in endemic areas become immune to malaria offers encouragement to the
idea of developing protective vaccines. However natural immunity is relatively inefficient …
idea of developing protective vaccines. However natural immunity is relatively inefficient …
[HTML][HTML] The Relationship between Anti-merozoite Antibodies and Incidence of Plasmodium falciparum Malaria: A Systematic Review and Meta-analysis
FJI Fowkes, JS Richards, JA Simpson… - PLoS medicine, 2010 - journals.plos.org
Background One of the criteria to objectively prioritize merozoite antigens for malaria
vaccine development is the demonstration that naturally acquired antibodies are associated …
vaccine development is the demonstration that naturally acquired antibodies are associated …
Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development
During blood-stage infection by Plasmodium falciparum, merozoites invade RBCs. Currently
there is limited knowledge of cellular and molecular invasion events, and no established …
there is limited knowledge of cellular and molecular invasion events, and no established …
[HTML][HTML] Identification and stoichiometry of glycosylphosphatidylinositol-anchored membrane proteins of the human malaria parasite Plasmodium falciparum* S
Most proteins that coat the surface of the extracellular forms of the human malaria parasite
Plasmodium falciparum are attached to the plasma membrane via …
Plasmodium falciparum are attached to the plasma membrane via …
[HTML][HTML] Progress and challenges for malaria vaccines
TL Richie, A Saul - Nature, 2002 - nature.com
Malaria causes much physical and economic hardship in tropical regions, particularly in
communities where medical care is rudimentary. Should a vaccine be developed, it is the …
communities where medical care is rudimentary. Should a vaccine be developed, it is the …
The future for blood‐stage vaccines against malaria
JS Richards, JG Beeson - Immunology and cell biology, 2009 - Wiley Online Library
Malaria is a leading cause of mortality and morbidity globally, and effective vaccines are
urgently needed. Malaria vaccine approaches can be broadly grouped as pre‐erythrocytic …
urgently needed. Malaria vaccine approaches can be broadly grouped as pre‐erythrocytic …
Band 3 is a host receptor binding merozoite surface protein 1 during the Plasmodium falciparum invasion of erythrocytes
VK Goel, X Li, H Chen, SC Liu… - Proceedings of the …, 2003 - National Acad Sciences
We report the molecular identification of a sialic acid-independent host–parasite interaction
in the Plasmodium falciparum malaria parasite invasion of RBCs. Two nonglycosylated …
in the Plasmodium falciparum malaria parasite invasion of RBCs. Two nonglycosylated …