Heterogeneity of vascular endothelial cells, de novo arteriogenesis and therapeutic implications in pancreatic neuroendocrine tumors
Arteriogenesis supplies oxygen and nutrients in the tumor microenvironment (TME), which
may play an important role in tumor growth and metastasis. Pancreatic neuroendocrine …
may play an important role in tumor growth and metastasis. Pancreatic neuroendocrine …
Protein kinase D1 signaling in angiogenic gene expression and VEGF-mediated angiogenesis
B Ren - Frontiers in cell and developmental biology, 2016 - frontiersin.org
Protein kinase D 1 (PKD-1) is a signaling kinase important in fundamental cell functions
including migration, proliferation, and differentiation. PKD-1 is also a key regulator of gene …
including migration, proliferation, and differentiation. PKD-1 is also a key regulator of gene …
[HTML][HTML] Diet-induced obesity links to ER positive breast cancer progression via LPA/PKD-1-CD36 signaling-mediated microvascular remodeling
L Dong, Y Yuan, C Opansky, Y Chen… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Obesity increases cancer risk including breast cancer (BC). However, the direct regulatory
mechanisms by which obesity promotes BC progression remain largely unknown. We show …
mechanisms by which obesity promotes BC progression remain largely unknown. We show …