Advances in cost-effective integrated spectrometers

A Li, C Yao, J Xia, H Wang, Q Cheng, R Penty… - Light: Science & …, 2022 - nature.com
The proliferation of Internet-of-Things has promoted a wide variety of emerging applications
that require compact, lightweight, and low-cost optical spectrometers. While substantial …

Near-infrared spectroscopy in bio-applications

KB Beć, J Grabska, CW Huck - Molecules, 2020 - mdpi.com
Near-infrared (NIR) spectroscopy occupies a specific spot across the field of bioscience and
related disciplines. Its characteristics and application potential differs from infrared (IR) or …

A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies

Y Roggo, P Chalus, L Maurer, C Lema-Martinez… - … of pharmaceutical and …, 2007 - Elsevier
Near-infrared spectroscopy (NIRS) is a fast and non-destructive analytical method.
Associated with chemometrics, it becomes a powerful tool for the pharmaceutical industry …

Application of near‐infrared spectroscopy for monitoring and control of cell culture and fermentation

AE Cervera, N Petersen, AE Lantz… - Biotechnology …, 2009 - Wiley Online Library
Near‐infrared (NIR) spectroscopy can potentially provide on‐line information on substrate,
biomass, product, and metabolite concentrations in fermentation processes, which could be …

Taking the pulse of bioprocesses: at-line and in-line monitoring of mammalian cell cultures

CF Shek, M Betenbaugh - Current Opinion in Biotechnology, 2021 - Elsevier
Highlights•Current advancements in at-line and in-line analytical tools have enabled the
refinement of existing tools.•Spectroscopic methods continue to be promising tools for …

In‐situ near infrared spectroscopy to monitor key analytes in mammalian cell cultivation

SA Arnold, J Crowley, N Woods… - Biotechnology and …, 2003 - Wiley Online Library
The use of in‐situ near infrared spectroscopy (NIRS) as a tool for monitoring four key
analytes in a CHO‐K1 animal cell culture was investigated. Previous work using on‐line …

Near infrared spectroscopy for bioprocess monitoring and control: current status and future trends

M Scarff, SA Arnold, LM Harvey… - Critical Reviews in …, 2006 - Taylor & Francis
ABSTRACT The development of Near Infrared Spectroscopy has paralleled that of the PC,
and the application of NIR in many industries has undergone explosive growth in recent …

A review of multivariate calibration methods applied to biomedical analysis

GM Escandar, PC Damiani, HC Goicoechea… - Microchemical …, 2006 - Elsevier
The determination of the contents of therapeutic drugs, metabolites and other important
biomedical analytes in biological samples is usually performed by using high-performance …

On-line estimation of biomass, glucose and ethanol in Saccharomyces cerevisiae cultivations using in-situ multi-wavelength fluorescence and software sensors

P Ödman, CL Johansen, L Olsson, KV Gernaey… - Journal of …, 2009 - Elsevier
Batch bioreactor cultivations using Saccharomyces cerevisiae at high (190–305gl− 1
glucose) or low (21–25gl− 1 glucose) gravity conditions were monitored on-line using multi …

Chip-scale sensor for spectroscopic metrology

C Yao, W Zhang, P Bao, J Ma, W Zhuo, M Chen… - Nature …, 2024 - nature.com
Miniaturized spectrometers hold great promise for in situ, in vitro, and even in vivo sensing
applications. However, their size reduction imposes vital performance constraints in meeting …