[HTML][HTML] Cuproptosis: A novel therapeutic target for overcoming cancer drug resistance
Y Wang, Y Chen, J Zhang, Y Yang, JS Fleishman… - Drug Resistance …, 2024 - Elsevier
Cuproptosis is a newly identified form of cell death driven by copper. Recently, the role of
copper and copper triggered cell death in the pathogenesis of cancers have attracted …
copper and copper triggered cell death in the pathogenesis of cancers have attracted …
Multifaceted carbonized metal–organic frameworks synergize with immune checkpoint inhibitors for precision and augmented cuproptosis cancer therapy
The discovery of cuproptosis, a copper-dependent mechanism of programmed cell death,
has provided a way for cancer treatment. However, cuproptosis has inherent limitations …
has provided a way for cancer treatment. However, cuproptosis has inherent limitations …
Transition-Metal-Based Nanozymes: Synthesis, Mechanisms of Therapeutic Action, and Applications in Cancer Treatment
Q Fu, C Wei, M Wang - ACS nano, 2024 - ACS Publications
Cancer, as one of the leading causes of death worldwide, drives the advancement of cutting-
edge technologies for cancer treatment. Transition-metal-based nanozymes emerge as …
edge technologies for cancer treatment. Transition-metal-based nanozymes emerge as …
Glutathione‐scavenging celastrol‐Cu nanoparticles induce self‐amplified cuproptosis for augmented cancer immunotherapy
S Lu, Y Li, Y Yu - Advanced Materials, 2024 - Wiley Online Library
Cuproptosis is a novel copper‐dependent programmed cell death. The efficacy of
cuproptosis is highly dependent on intracellular copper accumulation and counteracted by a …
cuproptosis is highly dependent on intracellular copper accumulation and counteracted by a …
Design of Near Infrared Light‐Powered Copper Phyllosilicate Nanomotors for Cuproptosis‐Based Synergistic Cancer Therapy
Cuproptosis, a newly discovered cell death pathway, has shown great potential in cancer
treatment. Herein, near‐infrared (NIR) light‐driven nanomotors (CuSiO3@ Au‐Pd NMs) are …
treatment. Herein, near‐infrared (NIR) light‐driven nanomotors (CuSiO3@ Au‐Pd NMs) are …
Dysregulated Wnt/β-catenin signaling confers resistance to cuproptosis in cancer cells
YT Liu, L Chen, SJ Li, WY Wang, YY Wang… - Cell Death & …, 2024 - nature.com
Cuproptosis is characterized by the aggregation of lipoylated enzymes of the tricarboxylic
acid cycle and subsequent loss of iron-sulfur cluster proteins as a unique copper-dependent …
acid cycle and subsequent loss of iron-sulfur cluster proteins as a unique copper-dependent …
[HTML][HTML] Biochemical hallmarks-targeting antineoplastic nanotherapeutics
J Han, H Dong, T Zhu, Q Wei, Y Wang, Y Wang, Y Lv… - Bioactive Materials, 2024 - Elsevier
Tumor microenvironments (TMEs) have received increasing attention in recent years as they
play pivotal roles in tumorigenesis, progression, metastases, and resistance to the traditional …
play pivotal roles in tumorigenesis, progression, metastases, and resistance to the traditional …
Biomimetic gold nanocages incorporating copper-human serum albumin for tumor immunotherapy via cuproptosis-lactate regulation
Cancer immunotherapy remains a significant challenge due to insufficient proliferation of
immune cells and the sturdy immunosuppressive tumor microenvironment. Herein, we …
immune cells and the sturdy immunosuppressive tumor microenvironment. Herein, we …
[HTML][HTML] Glucose oxidase: An emerging multidimensional treatment option for diabetic wound healing
Y Liao, Z Zhang, Y Zhao, S Zhang, K Zha, L Ouyang… - Bioactive Materials, 2025 - Elsevier
The healing of diabetic skin wounds is a complex process significantly affected by the
hyperglycemic environment. In this context, glucose oxidase (GOx), by catalyzing glucose to …
hyperglycemic environment. In this context, glucose oxidase (GOx), by catalyzing glucose to …
Cu Nanowires Trigger Efficient Cuproptosis via Special Intracellular Distribution and Excessive Cu Ion Release
Z Chen, Y Li, Y Yin, M Song, F Wang, G Jiang - Nano Letters, 2024 - ACS Publications
Cuproptosis, dependent on Cu overload, presents novel opportunities for cancer therapy.
Cu-based nanomaterials have shown excellent advantages for the intracellular delivery of …
Cu-based nanomaterials have shown excellent advantages for the intracellular delivery of …