Resveratrol as sensitizer in colorectal cancer plasticity

A Brockmueller, A Sajeev, L Koklesova… - Cancer and Metastasis …, 2024 - Springer
Despite tremendous medical treatment successes, colorectal cancer (CRC) remains a
leading cause of cancer deaths worldwide. Chemotherapy as monotherapy can lead to …

Resveratrol: biology, metabolism, and detrimental role on the tumor microenvironment of colorectal cancer

B Dariya, BP Girish, N Merchant, M Srilatha… - Nutrition …, 2023 - academic.oup.com
A substantial increase in colorectal cancer (CRC)–associated fatalities can be attributed to
tumor recurrence and multidrug resistance. Traditional treatment options, including radio …

Resveratrol modulates chemosensitisation to 5-FU via β1-integrin/HIF-1α Axis in CRC tumor microenvironment

A Brockmueller, S Girisa, AB Kunnumakkara… - International Journal of …, 2023 - mdpi.com
Frequent development of resistance to chemotherapeutic agents such as 5-flourouracil (5-
FU) complicates the treatment of advanced colorectal cancer (CRC). Resveratrol is able to …

Inhibition of Cancer Development by Natural Plant Polyphenols: Molecular Mechanisms

A Lyubitelev, V Studitsky - International Journal of Molecular Sciences, 2023 - mdpi.com
Malignant tumors remain one of the main sources of morbidity and mortality around the
world. A chemotherapeutic approach to cancer treatment poses a multitude of challenges …

Resveratrol in intestinal health and disease: focusing on intestinal barrier

Y Wang, C Hong, Z Wu, S Li, Y Xia, Y Liang, X He… - Frontiers in …, 2022 - frontiersin.org
The integrity of intestinal barrier determines intestinal homeostasis, which could be affected
by various factors, like physical, chemical, and biological stimuli. Therefore, it is of …

Inhibition and potential treatment of colorectal cancer by natural compounds via various signaling pathways

M Wang, X Liu, T Chen, X Cheng, H Xiao… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is a common type of malignant digestive tract tumor with a high
incidence rate worldwide. Currently, the clinical treatment of CRC predominantly include …

Targeting STAT proteins via computational analysis in colorectal cancer

B Dariya, S Muppala, G Srivani, S Momin… - Molecular and Cellular …, 2021 - Springer
Colorectal cancer (CRC) is the third most common cancer diagnosed worldwide making it a
serious global challenge. CRC progression results from dysregulated cytoplasmic …

Docking and molecular dynamic simulations of Mithramycin-A and Tolfenamic acid against Sp1 and survivin

CB Lambring, H Fiadjoe, SK Behera, R Basha - Process Biochemistry, 2024 - Elsevier
Therapeutic targeting of Sp1 transcription factor and survivin, are studied in various cancers
due to their consistent overexpression. These markers result in poorer cancer prognoses …

Understanding the Xylooligosaccharides Utilization Mechanism of Lactobacillus brevis and Bifidobacterium adolescentis: Proteins Involved and Their …

I Khangwal, S Skariyachan, A Uttarkar… - Molecular …, 2022 - Springer
Xylooligosaccharides having various degrees of polymerization such as xylobiose,
xylotriose, and xylotetraose positively affect human health by interacting with gut proteins …

Natural Stilbenes: Their Role in Colorectal Cancer Prevention, DNA Methylation, and Therapy

V Fialková, H Ďúranová, P Borotová… - Nutrition and …, 2024 - Taylor & Francis
The resistance of colorectal cancer (CRC) to conventional therapeutic modalities, such as
radiation therapy and chemotherapy, along with the associated side effects, significantly …