Targeting Trojan Horse leukocytes for HIV prevention

DJ Anderson, JA Politch, AM Nadolski, CD Blaskewicz… - Aids, 2010 - journals.lww.com
Targeting Trojan Horse leukocytes for HIV prevention : AIDS Targeting Trojan Horse leukocytes
for HIV prevention : AIDS Log in or Register Subscribe to journalSubscribe Get new issue …

Increases in human papillomavirus detection during early HIV infection among women in Zimbabwe

RG Nowak, PE Gravitt, CS Morrison… - Journal of Infectious …, 2011 - academic.oup.com
Background. Individuals who acquire human immunodeficiency virus (HIV) may experience
an immediate disruption of genital tract immunity, altering the ability to mount a local and …

Characteristics and quantities of HIV host cells in human genital tract secretions

JA Politch, J Marathe… - The Journal of infectious …, 2014 - academic.oup.com
Human immunodeficiency virus (HIV)–infected leukocytes have been detected in genital
secretions from HIV-infected men and women and may play an important role in the sexual …

Impact of human immunodeficiency virus 1 infection and inflammation on the composition and yield of cervical mononuclear cells in the female genital tract

NN Nkwanyana, PP Gumbi, L Roberts, L Denny… - …, 2009 - Wiley Online Library
Cervical cytobrush sampling is a relatively non‐invasive method for obtaining mucosal cells
from the female genital tract. To define mucosal immune cells sampled by cervical …

Early HIV-1 infection is associated with reduced frequencies of cervical Th17 cells

LR McKinnon, B Nyanga, CJ Kim, P Izulla… - JAIDS Journal of …, 2015 - journals.lww.com
Background: The hallmark of HIV infection is progressive but variable rates of systemic and
mucosal CD4 depletion, leading to immunodeficiency. The impact of early HIV infection on …

CCR5 expression is elevated on endocervical CD4+ T cells in healthy postmenopausal women

AL Meditz, KL Moreau, S MaWhinney… - JAIDS Journal of …, 2012 - journals.lww.com
Background: New HIV-1 infections are increasing in older American women largely through
heterosexual transmission. Activated CD4+ T cells and CCR5 expression are linked to HIV-1 …

[HTML][HTML] ART influences HIV persistence in the female reproductive tract and cervicovaginal secretions

R Olesen, MD Swanson, M Kovarova… - The Journal of …, 2016 - Am Soc Clin Investig
The recently completed HIV prevention trials network study 052 is a landmark collaboration
demonstrating that HIV transmission in discordant couples can be dramatically reduced by …

Foreskin inflammation is associated with HIV and herpes simplex virus type-2 infections in Rakai, Uganda

KE Johnson, ME Sherman, V Ssempiija, AAR Tobian… - Aids, 2009 - journals.lww.com
Design: We assessed foreskin inflammation associated with HIV and herpes simplex virus
type 2 (HSV-2) in circumcised men. Methods: Foreskin tissues were assessed in 97 HIV …

Depletion of CD4+ T cells in semen during HIV infection and their restoration following antiretroviral therapy

JA Politch, KH Mayer, DJ Anderson - JAIDS Journal of Acquired …, 2009 - journals.lww.com
Background: Information concerning the effects of HIV-1 infection, disease progression, and
antiretroviral therapy (ART) on male genital white blood cell (WBC) profiles could provide …

Development of a pigtail macaque model of sexually transmitted infection/HIV coinfection using Chlamydia trachomatis, Trichomonas vaginalis, and SHIVSF162P3

T Henning, Y Fakile, C Phillips… - Journal of medical …, 2011 - Wiley Online Library
Abstract Background Sexually transmitted infections (STIs) are associated with an increased
risk of HIV infection. To model the interaction between STIs and HIV infection, we evaluated …