[HTML][HTML] Sepsis-mediated renal dysfunction: pathophysiology, biomarkers and role of phytoconstituents in its management

A Balkrishna, S Sinha, A Kumar, V Arya… - Biomedicine & …, 2023 - Elsevier
Sepsis has evolved as an enormous health issue amongst critically ill patients. It is a major
risk factor that results in multiple organ failure and shock. Acute kidney injury (AKI) is one of …

The effects of exercise on kidney injury: the role of SIRT1

N Sabet, Z Soltani, M Khaksari - Molecular biology reports, 2022 - Springer
In patients with kidney injury, muscle mass and strength decrease with altered muscle
protein synthesis and degradation along with complications such as inflammation and low …

Nontoxic-dose deoxynivalenol aggravates lipopolysaccharides-induced inflammation and tight junction disorder in IPEC-J2 cells through activation of NF-κB and …

L Ge, Z Lin, G Le, L Hou, X Mao, S Liu, D Liu… - Food and Chemical …, 2020 - Elsevier
Lipopolysaccharide (LPS) is the key factor in various intestinal inflammation which could
disrupt the epithelial barrier function. Deoxynivalenol (DON), a well-known mycotoxin, can …

Roles and molecular mechanisms of physical exercise in sepsis treatment

Y Wu, X Guo, Y Peng, Z Fang, X Zhang - Frontiers in Physiology, 2022 - frontiersin.org
Physical exercise is a planned, purposeful action to keep a healthy lifestyle and improve
physical fitness. Physical exercise has been widely used as a non-pharmacological …

GPR120 ameliorates apoptosis and inhibits the production of inflammatory cytokines in renal tubular epithelial cells

D Zhi, M Zhang, J Lin, P Liu, M Duan - Inflammation, 2021 - Springer
Acute kidney injury (AKI) is the most common complication of sepsis with a high mortality
rate. In this study, we focus on the renal injury caused by the immune response of renal …

Protective mechanisms of Leontopodium leontopodioides extracts on lipopolysaccharide-induced acute kidney injury viathe NF-κB/NLRP3 pathway

BAI Xue, MA Qianqian, LI Qi, YIN Meizhen… - Chinese Journal of …, 2023 - Elsevier
Sepsis-induced uncontrolled systemic inflammatory response syndrome (SIRS) is a critical
cause of multiple organ failure. Acute kidney injury (AKI) is one of the most serious …

[HTML][HTML] Baker's yeast beta glucan supplementation was associated with an improved innate immune mRNA expression response after exercise

BK McFarlin, EA Bridgeman, JH Curtis, JL Vingren… - Methods, 2024 - Elsevier
Beta glucans are found in many natural sources, however, only Baker's Yeast Beta Glucan
(BYBG) has been well documented to have structure–function effects that are associated …

Effects of gallic acid and physical training on liver damage, force, and anxiety in obese mice: Hepatic modulation of Sestrin 2 (SESN2) and PGC-α expression

JN Sousa, BV de Oliveira Sousa, EP Dos Santos… - Gene, 2024 - Elsevier
Obesity and overweight are multifactorial diseases affecting more than one-third of the
world's population. Physical inactivity contributes to a positive energy balance and the onset …

Preconditioning by Moderate-Intensity Exercise Prevents Gentamicin-Induced Acute Kidney Injury

EG Fonseca, AP Araújo-Ferreira… - … Journal of Sports …, 2024 - thieme-connect.com
A strict correlation among proximal tubule epithelial cell dysfunction, proteinuria, and
modulation of the Renin-Angiotensin System and Kalikrein-Kinin System are crucial factors …

Renoprotective Effect Of Sambiloto (Andrographis Paniculata) Leaf Extract On Lipopolysaccharide–Induced Septic Rats

ABB Prananta, NS Widyastiti, A Ariosta… - … of Biomedicine and …, 2023 - ejournal2.undip.ac.id
Background: Associated with sepsis is the illness known as acute kidney injury (AKI). AKI
may be mediated by uric acid, and blood creatinine levels can be utilized to diagnose the …