The role of nicotine and flavor in the abuse potential and appeal of electronic cigarettes for adult current and former cigarette and electronic cigarette users: a …

MS Gades, A Alcheva, AL Riegelman… - Nicotine and Tobacco …, 2022 - academic.oup.com
Introduction Many adult cigarette smokers use electronic cigarettes (e-cigarettes) to cut
down on or quit smoking cigarettes. E-cigarettes with higher abuse potential and appeal …

Ice flavours and non-menthol synthetic cooling agents in e-cigarette products: a review

AM Leventhal, AP Tackett, L Whitted… - Tobacco …, 2023 - tobaccocontrol.bmj.com
E-cigarettes with cooling flavours have diversified in ways that complicate tobacco control
with the emergence of:(1) Ice-hybrid flavours (eg,'Raspberry Ice') that combine cooling and …

Effect of exposure to e-cigarettes with salt vs free-base nicotine on the appeal and sensory experience of vaping: a randomized clinical trial

AM Leventhal, DR Madden, N Peraza… - JAMA network …, 2021 - jamanetwork.com
Importance Alkaline free-base nicotine is bitter and a respiratory irritant. High-nicotine
electronic cigarette (e-cigarette) products contain acid additives that change nicotine from a …

[HTML][HTML] Abuse liability assessment of the JUUL system in four flavors relative to combustible cigarette, nicotine gum and a comparator electronic nicotine delivery …

NI Goldenson, AR Buchhalter, EM Augustson… - Drug and Alcohol …, 2020 - Elsevier
Background The abuse liability of the JUUL System (JS) in four flavors were evaluated
compared to combustible cigarettes, nicotine gum, and a comparator electronic nicotine …

Expanding the e-liquid flavor wheel: classification of emerging e-liquid flavors in online vape shops

S Ma, Z Qiu, Q Yang, JFP Bridges, J Chen… - International journal of …, 2022 - mdpi.com
Introduction: Electronic cigarettes are the most popular tobacco product among US youth,
and over 80% of current youth users of e-cigarettes use flavored e-cigarettes, with fruit …

Dose–response effects of two nicotine salt formulations on electronic cigarette appeal and sensory attributes

DH Han, M Wong, N Peraza, EA Vogel… - Tobacco …, 2024 - tobaccocontrol.bmj.com
Objectives Various organic acids are used to create nicotine salt formulations, which may
improve the appeal and sensory experience of vaping electronic cigarettes (e-cigarettes) …

History repeats itself: role of characterizing flavors on nicotine use and abuse

T Patten, M De Biasi - Neuropharmacology, 2020 - Elsevier
The popularity of e-cigarettes has skyrocketed in recent years, and most vapers use flavored
e-cigarette products. Consumption of flavored e-cigarettes exceeds that of combustible …

Pharmacokinetic and subjective assessment of prototype JUUL2 electronic nicotine delivery system in two nicotine concentrations, JUUL system, IQOS, and …

NI Goldenson, EM Augustson, J Chen, S Shiffman - Psychopharmacology, 2022 - Springer
Rationale Electronic nicotine delivery systems and heated tobacco products are
noncombustible alternatives for adult smokers. Evidence suggests sufficient nicotine …

Electronic nicotine delivery systems: an updated policy statement from the American Association for Cancer Research and the American Society of Clinical Oncology

RS Herbst, D Hatsukami, D Acton, M Giuliani… - Clinical Cancer …, 2022 - AACR
Combustible tobacco use has reached historic lows, demonstrating the importance of
proven strategies to reduce smoking since publication of the 1964 Surgeon General's report …

[HTML][HTML] Abuse liability assessment of the JUUL system in two nicotine concentrations compared to combustible cigarette, nicotine gum and comparator electronic …

NI Goldenson, AR Buchhalter, EM Augustson… - Drug and Alcohol …, 2020 - Elsevier
Background To assess the abuse liability of the JUUL System (JS) in 5.0%(59 mg/mL) and
3.0%(35 mg/mL) nicotine concentrations. Methods Adult smokers (N= 146; 45.9% female; …