Multifunctional Cytochrome c: Learning New Tricks from an Old Dog

D Alvarez-Paggi, L Hannibal, MA Castro… - Chemical …, 2017 - ACS Publications
Cytochrome c (cyt c) is a small soluble heme protein characterized by a relatively flexible
structure, particularly in the ferric form, such that it is able to sample a broad conformational …

Licensed to kill: mitochondria, chloroplasts, and cell death

O Van Aken, F Van Breusegem - Trends in plant science, 2015 - cell.com
Programmed cell death (PCD) is crucial in plant organogenesis and survival. In this review
the involvement of mitochondria and chloroplasts in PCD execution is critically assessed …

Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition

CA Elena-Real, A Díaz-Quintana… - Cell death & …, 2018 - nature.com
Apoptosis is a highly regulated form of programmed cell death, essential to the development
and homeostasis of multicellular organisms. Cytochrome c is a central figure in the activation …

Oxidative stress is tightly regulated by cytochrome c phosphorylation and respirasome factors in mitochondria

A Guerra-Castellano, A Díaz-Quintana… - Proceedings of the …, 2018 - National Acad Sciences
Respiratory cytochrome c has been found to be phosphorylated at tyrosine 97 in the
postischemic brain upon neuroprotective insulin treatment, but how such posttranslational …

Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid–liquid phase separation

K González-Arzola, A Díaz-Quintana… - Nature structural & …, 2022 - nature.com
The regular functioning of the nucleolus and nucleus-mitochondria crosstalk are considered
unrelated processes, yet cytochrome c (C c) migrates to the nucleus and even the nucleolus …

Mitochondrial respiration and energy production under some abiotic stresses

S Aliyari Rad, Z Dehghanian, B Asgari Lajayer… - Journal of Plant Growth …, 2021 - Springer
In plants, mitochondrial respiration supplies energy for biosynthesis, and its equilibrium with
photosynthesis determines the accumulation rate of plant biomass. Though the …

[HTML][HTML] Plant defence mechanisms against mycotoxin Fumonisin B1

N Iqbal, Z Czékus, P Poór, A Ördög - Chemico-biological interactions, 2021 - Elsevier
Abstract Fumonisin B1 (FB1) is the most harmful mycotoxin which prevails in several crops
and affects the growth and yield as well. Hence, keeping the alarming consequences of FB1 …

New moonlighting functions of mitochondrial cytochrome c in the cytoplasm and nucleus

K González‐Arzola, A Velázquez‐Cruz… - FEBS …, 2019 - Wiley Online Library
Cytochrome c (Cc) is a protein that functions as an electron carrier in the mitochondrial
respiratory chain. However, Cc has moonlighting roles outside mitochondria driving the …

Stress signalling dynamics of the mitochondrial electron transport chain and oxidative phosphorylation system in higher plants

C Dourmap, S Roque, A Morin, D Caubrière… - Annals of …, 2020 - academic.oup.com
Background Mitochondria play a diversity of physiological and metabolic roles under
conditions of abiotic or biotic stress. They may be directly subjected to physico-chemical …

Emerging roles of chromatin in the maintenance of genome organization and function in plants

Z Vergara, C Gutierrez - Genome Biology, 2017 - Springer
Chromatin is not a uniform macromolecular entity; it contains different domains
characterized by complex signatures of DNA and histone modifications. Such domains are …